PhyloSuite v2: The development of an all-in-one, efficient and visualization-oriented suite for molecular dating analysis and other advanced features. [PDF]
Zhao D +14 more
europepmc +1 more source
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey +2 more
wiley +1 more source
Spatiotemporal dynamics of age-related genes and the regulatory network of LaAGL2-3 in Larix kaempferi (Lamb.) Carr. based on the latest genome annotation. [PDF]
Liao TQ, Luo AJ, Ye ZL, Li W.
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Protein structure-informed bacteriophage genome annotation with Phold. [PDF]
Bouras G +13 more
europepmc +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
InsectBase 3.0: a comprehensive multi-omics resource for insects. [PDF]
Wang Z +10 more
europepmc +1 more source
SEdb 3.0: a comprehensive super-enhancer database across multiple species. [PDF]
Song S +12 more
europepmc +1 more source
Reference-guided draft genome assembly of the slender walking catfish, <i>Prophagorus nieuhofii</i>. [PDF]
Imron I +7 more
europepmc +1 more source
Functional and Structure Prediction of Hypothetical Proteins From <i>Listeria aquatica</i> FSL S10-1188: Bioinformatics Approaches. [PDF]
Abdallah MM +3 more
europepmc +1 more source

