Results 221 to 230 of about 393,868 (257)

PhyloSuite v2: The development of an all-in-one, efficient and visualization-oriented suite for molecular dating analysis and other advanced features. [PDF]

open access: yesImeta
Zhao D   +14 more
europepmc   +1 more source

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

open access: yesFEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey   +2 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Protein structure-informed bacteriophage genome annotation with Phold. [PDF]

open access: yesNucleic Acids Res
Bouras G   +13 more
europepmc   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

InsectBase 3.0: a comprehensive multi-omics resource for insects. [PDF]

open access: yesNucleic Acids Res
Wang Z   +10 more
europepmc   +1 more source

SEdb 3.0: a comprehensive super-enhancer database across multiple species. [PDF]

open access: yesNucleic Acids Res
Song S   +12 more
europepmc   +1 more source

Reference-guided draft genome assembly of the slender walking catfish, <i>Prophagorus nieuhofii</i>. [PDF]

open access: yesF1000Res
Imron I   +7 more
europepmc   +1 more source

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