Results 251 to 260 of about 2,847,669 (316)

jdispatcher-viewers: interactive visualizations of sequence similarity search results and domain predictions. [PDF]

Bioinform Adv
Madeira F, Lee J, Madhusoodanan N, Eusebi A, Niewielska A, Butcher S.   +5 more
europepmc   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

GOBeacon: An ensemble model for protein function prediction enhanced by contrastive learning. [PDF]

Protein Sci
Lin W, Miller D, Gu Z, Orengo C.
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Conformational Analysis and Structure-Altering Mutations of the HIV-1 Frameshifting Element. [PDF]

Int J Mol Sci
Newton K, Yan S, Schlick T.
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Molecular Recognition and Modification Strategies of Umami Dipeptides with T1R1/T1R3 Receptors. [PDF]

Molecules
Hu K, Sun G, Yu W, Zhang M, Wang S, Cao Y, Hu D, Liang L, He G, Hu J, Liu W.   +10 more
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Whole genome sequence of a virulent and multidrug resistant Staphylococcus aureus strain MD02 isolated from a diabetic foot ulcer in Uganda. [PDF]

BMC Genom Data
Makeri D, Eilu E, Odoki M, Adebayo IA, Maghembe R, Abubakar M, Muhwezi R, Pius T, Dilli PP, Akinola SA, Agwu E.   +10 more
europepmc   +1 more source

The phylogeny of the complex (Lepidoptera: Sphingidae): Molecular evidence from sequence data and ISSR-PCR fingerprints

, 2005
Anna K. Hundsdoerfer, Ian J. Kitching, Michaël Wink   +2 more
openalex   +1 more source