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Molecular Epidemiology Database for Sequence Management and Data Mining

2017
A central database to aggregate sequence information from a range of epidemiological aspects including HTLV-1 pathogenesis, origin, and evolutionary dynamic would be useful to scientists and physicians worldwide. This Chapter describes two online tools for studies related to HTLV-1, the HTLV-1 Molecular Epidemiology Database and the HTLV-1 Subtyping ...
Thessika Hialla Almeida, Araújo   +2 more
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Bayesian Hypothesis Testing of Four-Taxon Topologies Using Molecular Sequence Data

Biometrics, 1996
The reconstruction of phylogenetic trees from molecular sequences presents unusual problems for statistical inference. For example, three possible alternatives must be considered for four taxa when inferring the correct unrooted tree (referred to as a topology).
Sinsheimer, Janet S.   +2 more
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Evolutionary analysis of molecular sequence data

2007
Abstract In the 140 years since Darwin’s Origin of Species was published, evolutionary ideas have formed an important part of the theoretical framework of biological research, but their practical consequences have been few for most of that period.
Hughes, A., Da Silva, J., Verra, F.
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Quantitation of Molecular Pathway Activation Using RNA Sequencing Data

2019
Intracellular molecular pathways (IMPs) control all major events in the living cell. IMPs are considered hotspots in biomedical sciences and thousands of IMPs have been discovered for humans and model organisms. Knowledge of IMPs activation is essential for understanding biological functions and differences between the biological objects at the ...
Nicolas, Borisov   +3 more
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Molecular Sequence Data-Bases and Their Uses

1992
Abstract Introduction There are many aspects of nucleic acid and amino acid sequences pertinent to protein engineering. For example, promoters and other types of non-coding regulatory DNA and RNA can be studied and manipulated with the purpose of designing transcription and translation units for maximal expression of natural or mutated ...
Mark S Boguski   +2 more
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Analysis of recombination in molecular sequence data

2008
Wir präsentieren Recco, eine neue und schnelle Methode zur Analyse von Rekombinationen in multiplen Alignments. Recco basiert auf einem dynamischen Programm, welches eine Sequenz im Alignment durch die anderen Sequenzen im Alignment rekonstruiert, wobei die Operatoren Mutation und Rekombination erlaubt sind.
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Estimation of Divergence Times from Molecular Sequence Data

2005
“A comparison of the structures of homologous proteins (i.e., proteins with the same kinds of biological activity or function) from different species is important, therefore, for two reasons. First, the similarities found give a measure of the minimum structure for biological function.
Jeffrey L. Thorne, Hirohisa Kishino
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Fixed Character States and the Optimization of Molecular Sequence Data

Cladistics, 1999
A method is proposed to optimize molecular sequence data that does not employ multiple sequence alignment. This method treats entire homologous contiguous stretches of sequence data as individual characters. This sequence is treated as the homologous unit employed in phylogeny reconstruction.
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Molecular sequence data resolves basal divergences within Simuliidae (Diptera)

Systematic Entomology, 2000
Summary Basal divergences within Simuliidae are inferred from portions of the large nuclear ribosomal subunit (28S), elongation factor‐one alpha (EF‐1α), dopa decarboxylase (DDC), phosphoenolpyruvate carboxykinase (PEPCK), the small mitochondrial ribosomal subunit (12S) and subunit two of NADH dehydrogenase (ND2).
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Short Introduction to Phylogenetic Analysis of Molecular Sequence Data

2018
Phylogeny is a model of the relationships between organisms, genes, protein, and other structures based on common ancestry. It is also used for epidemiological investigations and analysis of parallel evolution between host and parasite. Phylogenetic trees can be visualized as dendrograms or as radial trees.
Henrik Christensen, John Elmerdahl Olsen
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