Results 41 to 50 of about 128,137 (298)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Atmospheric composition affects heat- and mass-transfer processes [PDF]
For environmental control system functions sensitive to atmospheric composition, components are test-operated in helium-oxygen and nitrogen-oxygen mixtures, pure oxygen, and air.
Blakely, R. L., Nelson, W. G.
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Purification train produces ultrapure hydrogen gas [PDF]
Three-stage purification train produces ultrapure hydrogen gas at 1000 psi from K-bottles of high-purity hydrogen.
Walter, R. J.
core +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Cu-Mn doped beta zeolite catalyst was easily prepared for efficient total oxidation of propane
In this paper, CuMn doped catalysts were prepared by using SiO2, γ-Al2O3 and Beta molecular sieve as carriers, and propane catalytic degradation experiments were carried out.
Chunyu Li +3 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Selective Crystallization of Silicoalumophosphate Sapo-11 With A Micromesoporous Structure
: The authors have proposed a method for the selective crystallization of a SAPO-11 silicoaluminophosphate molecular sieve with a micro-mesoporous structure.
Zulfiya Khayrullina +3 more
doaj +1 more source
Difunctional polyisobutylene prepared by polymerization of monomer on molecular sieve [PDF]
Process yields difunctional isobutylene polymers ranging in molecular weight from 1150 to 3600. These polymers have the potential for copolymerization and cross-linking with other monomers to form elastomeric ...
Midler, J. A., Jr.
core +1 more source
Synthesis of titanium-containing ZSM-48 [PDF]
Titanium-containing ZSM-48 is synthesized with silicon to titanium ratios of 26 or larger; changes in unit cell volume and IR data show that titanium is incorporated into framework ...
Davis, Mark E. +2 more
core +1 more source

