Results 101 to 110 of about 4,989,468 (303)

Progress made towards context-free molecular structure determination from isotopologue rotational spectroscopy [PDF]

, 2020
Made available in DSpace on 2020-06-26T03:04:41Z (GMT). No. of bitstreams: 2 4667.pdf: 19957 bytes, checksum: 171c23498d0309af3c250a09dc5740e1 (MD5) license.txt: 4802 bytes, checksum: 58353f9dd6876860dd5221f3d7872a95 (MD5) Previous issue date ...
Yeh, Lia
core  

Molecular chirality: enantiomer differentiation by high-resolution spectroscopy [PDF]

, 2014
I have demonstrated that triple resonance performed on a three-rotational-level system of a chiral molecule of C$_{1}$ symmetry exhibits signals opposite in phase for different enantiomers, thereby making enantiomer differentiation possible by microwave ...
Hirota, Eizi, Eizi Hirota
core   +1 more source

Stereoelectronic and hydrogen-bonding effects on hydroxyproline conformation

Communications Chemistry
Collagen’s structural integrity and biological function derive from its characteristic triple helix, governed by a unique amino acid sequence containing the rare residue (2S,4R)-hydroxyproline (4R-Hyp).
Fumiki Matsumura, Pablo Gómez Argudo, Mischa Bonn, Giulia Giubertoni, Johannes Hunger   +4 more
doaj   +1 more source

Analysis of riboflavin/ultraviolet a corneal cross-linking by molecular spectroscopy. [PDF]

Heliyon, 2023
Melcher S, Zimmerer C, Galli R, Golde J, Herber R, Raiskup F, Koch E, Steiner G.   +7 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Impedance spectroscopy for cellular and biomolecular analysis

, 2009
The application of microfabrication technology to molecular and cell biology has motivated the rapid development of a novel class of microdevices collectively known as ‘Lab On a Chip’ devices.Impedance spectroscopy is a non-invasive, label-free ...
Malleo, Daniele
core   +1 more source

Label-free differentiation of human pancreatic cancer, pancreatitis, and normal pancreatic tissue by molecular spectroscopy. [PDF]

J Biomed Opt, 2022
Teske C, Kahlert C, Welsch T, Liedel K, Weitz J, Uckermann O, Steiner G.   +6 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Electron heating and thermal relaxation of gold nanorods revealed by two-dimensional electronic spectroscopy

Nature Communications, 2018
Electron dynamics in plasmonic nanoparticles are often studied with transient absorption spectroscopy. Here, Lietard et al. apply two-dimensional electronic spectroscopy, a method generally used for molecular spectroscopy, to study ultrafast nonlinear ...
Aude Lietard, Cho-Shuen Hsieh, Hanju Rhee, Minhaeng Cho   +3 more
doaj   +1 more source