Results 161 to 170 of about 4,508,859 (303)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Mutations of SARS-CoV-2 RBD May Alter Its Molecular Structure to Improve Its Infection Efficiency [PDF]

, 2021
Ahmed L. Alaofi, Mudassar Shahid
openalex   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Towards the Development of Effective Antioxidants-The Molecular Structure and Properties-Part 2. [PDF]

Molecules
Lewandowska H, Świsłocka R, Priebe W, Lewandowski W, Orzechowska S.   +4 more
europepmc   +1 more source

3-D CMZ II: Hierarchical Structure Analysis of the Central Molecular Zone [PDF]

Cara Battersby, Daniel L. Walker, Ashley T. Barnes, Adam Ginsburg, Dani Lipman, Danya Alboslani, H Perry Hatchfield, John Bally, Simon C. O. Glover, Jonathan D. Henshaw, K. Immer, Ralf S. Klessen, Steven N. Longmore, Elisabeth A. C. Mills, S. Molinari, Rowan J. Smith, Mattia C. Sormani, Robin G. Treß, Qizhou Zhang   +18 more
openalex   +1 more source

Molecular Structure Investigations by Electron Diffraction Method. II. The Molecular Structure of Ethylene Chlorohydrin [PDF]

, 1956
Mashio Yamaha
openalex   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Molecular structure and nickel-binding capacity of Proteus mirabilis UreE. [PDF]

Acta Crystallogr D Struct Biol
Pan J, Mueller SL, Tasneem N, Wu Y, Furlong EJ.   +4 more
europepmc   +1 more source

Uncovering Novel VIM-2 Inhibitors from Fungal Sources Using Structure-Based Screening and Molecular Dynamics Approaches [PDF]

Sandip Dolui, Amartya Mitra, Kaushik Biswas, Kamalika Mazumder   +3 more
openalex   +1 more source

The Crystal and Molecular Structure of Methyl 6-O-Acetyl-beta-D-galactopyranoside. [PDF]

, 1973
Börje Lindberg, Per J. Garegg, Carl‐Gunnar Swahn, Steen Skaarup, Riitta Aaltonen, Carl‐Gunnar Swahn   +5 more
openalex   +1 more source