Results 161 to 170 of about 2,182,736 (268)

13C-Labelled Folates as NMR Probes of the Binding of Folate to Bacterial Dihydrofolate Reductases

Pteridines, 1991
Cheung H. T. A., Chau D. D., Morrison J. F., Birdsall B., Feeney J.   +4 more
doaj   +1 more source

Machine learning models for prediction of (Pro)cathepsin-glycosaminoglycan binding free energies based on molecular structure. [PDF]

Comput Struct Biotechnol J
Bojarski KK, Quoika PK, Zacharias M.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Interpretable multitask deep learning models for odor perception based on molecular structure. [PDF]

Curr Res Food Sci
Iwata H.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Investigation of N-(2-oxo-2H-chromen-3-carbonyl)cytisine's Molecular Structure in Solution. [PDF]

Molecules
Kopbalina K, Adekenova A, Shaimerdenova Z, Kairatova Z, Shakarimova K, Pankin D, Smirnov M, Kishkentayeva A, Artykbayeva M, Jalmakhanbetova R.   +9 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Influence of Molecular Structure of POM on Processability Within Metal Injection Molding. [PDF]

Polymers (Basel)
Forstner T, Cholewa S, Früh T, Drummer D.   +3 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Machine Learning-Assisted Design of Molecular Structure of Diphenylamine Antioxidants. [PDF]

ACS Omega
Song M, Hu Z, Wang M, Jia S, Cao F, Duan L, Qin Q, Jiao M, Wang R.   +8 more
europepmc   +1 more source