Results 171 to 180 of about 4,508,859 (303)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

"QuickStainer": a rapid negative staining device for improved preservation of molecular structure. [PDF]

J Struct Biol
Nguyen V, Gautam R, Somavarapu AK, Dutta D, Patra A, Ge J, Yengo CM, Padrón R, Craig R.   +8 more
europepmc   +1 more source

Correlating melt structure, viscosity, and Ca content in Mg–Ca alloys via molecular dynamics [PDF]

Dengyuan Qi, Ang Zhang, Lijun Zhang, Tao Jiang, Feng He, Jun Wang, Zehua Li, Xiao Li, Jiangfeng Song, Bin Jiang   +9 more
openalex   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Density Functional Theory Analysis of Luteolin Molecular Structure and Spectrum. [PDF]

ACS Omega
Zheng Y, Zhang Y, Wang Z, Zhang Y.
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Generative modeling enables molecular structure retrieval from Coulomb explosion imaging. [PDF]

Nat Commun
Li X, Jahnke T, Boll R, Han J, Xu M, Meyer M, Piancastelli MN, Rolles D, Rudenko A, Trinter F, Wolf TJA, Thayer JB, Cryan JP, Ermon S, Ho PJ.   +14 more
europepmc   +1 more source

Molecular structure-affinity relationship of dietary flavonoids for bovine serum albumin [PDF]

, 2011
Jian Shi, Hui Cao
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Probing the molecular structure at graphite-water interfaces by correlating 3D-AFM and SHINERS. [PDF]

Nat Commun
Bonagiri LKS, Arvelo DM, Zhao F, Kim J, Ai Q, Zhou S, Panse KS, Garcia R, Zhang Y.   +8 more
europepmc   +1 more source