Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
THE MOLECULAR STRUCTURE OF {2,6[P(O)(O-i-Pr)2]2-4-t-BuC6H2}SiPh3 [PDF]
K. Peveling +2 more
openalex +1 more source
Frontispiece: Organic molecular aggregates: From aggregation structure to emission property [PDF]
Suqian Ma +5 more
openalex +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Molecular structure of the functionalized bismuth alkoxide Bi[OC(CH 2 NMe 2 ) 3 ] 3 [PDF]
Gabriele Kociok‐Köhn +2 more
openalex +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
The Crystal and Molecular Structure of the Dehydrated Tetramer of 1,2-Dimethyldisilanetetraol, (CH3)8Si8O8 [PDF]
Taiichi Higuchi, Akira Shimada
openalex +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Crystal and Molecular Structure of ω-Amino Acids, ω-Aminosulfonic Acids and Their Derivatives. I. The Crystal and Molecular Structure of γ-Guanidinobutyric Acid Hydrochloride and Hydrobromide [PDF]
Tomie Maeda +2 more
openalex +1 more source
Molecular Structure of Xanthocidin
Tosio SAKURAI +2 more
openaire +2 more sources

