Results 81 to 90 of about 2,165,084 (288)

Ubiquitin ligase RNF20 coordinates sequential adipose thermogenesis with brown and beige fat-specific substrates

open access: yesNature Communications
In mammals, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) execute sequential thermogenesis to maintain body temperature during cold stimuli.
Yong Geun Jeon   +18 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Crystal and molecular structure of some cubane-like tetranuclear molybdenum clusters [PDF]

open access: bronze, 1987
Jie Huang   +7 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

26 Towards an HIV functional cure with CAR-T cells: elucidating mechanisms underlying the extremely high potency of bispecific anti-HIV CARs designed for optimal activity and minimal immunogenicity

open access: yesJournal of Virus Eradication, 2017
M.H. Ghanem   +8 more
doaj   +1 more source

Experimental and modeling studies for the simultaneous removal anionic dyes in single and binary systems using activated clay

open access: yesScientific Reports
The treatment of dyes and pigments represents a significant environmental challenge worldwide. This study investigates the adsorption of Bemacid Blue (BB) and Congo Red (CR) using hydrochloric acid-activated bentonite clay treated at an 8 N concentration
Hadjer Bousemat   +7 more
doaj   +1 more source

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