Results 61 to 70 of about 12,307,698 (317)
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
, 2020 This Special Issue of International Journal of Molecular Sciences (IJMS) contains 7 reviews and 12 original research papers written by a panel of experts who highlight recent advances in molecular structure and cellular function of purinergic P2 ...
Hana Zemkova
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Structure and mechanism of the HECT ligase HECTD3
Nature CommunicationsHECT E3 ligases regulate many cellular processes, yet how they recognise their substrates and synthesise specific types of poly-ubiquitin chains is still incompletely understood.
Jessica Huber +5 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Targeted Stimulation of Micropores by CS2 Extraction on Molecular of Coal [PDF]
The targeted stimulation of micropores based on the transformation of coal’s molecular structure is proposed due to the chemical properties and difficult-to-transform properties of micropores.
Zhen Zhang +11 more
core +1 more source
, 2020 The objective of the studies was to synthesize and characterize new mono- and diesters with an imidazoquinolin-2-one ring with the use of 2,3-dihydro-2-thioxo-1H-imidazo[4 ,5-c]-quinolin-4(5H)-ones and ethyl bromoacetate.
Iwona Zarzyka +5 more
core +1 more source
Molecular structure and conformational composition of methyl chloroacetate: An electron-diffraction and ab initio molecular orbital investigation [PDF]
, 2010 The molecular structure and conformational composition of methyl chloroacetate, H2ClCC(O)OCH3, have been determined by gas-phase electron-diffraction (GED), using results from ab initio molecular orbital calculations (HF, MP2 and MP3/6-311+G(d,p)) to ...
Hagen, Kolbjørn +5 more
core +1 more source
Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition
Nature Communications, 2018 NS1 of influenza A virus inhibits TRIM25 activity, which is an E3 ligase important for induction of the interferon response. Here, Koliopoulos et al. present structures of TRIM25 and NS1 and show how NS1 binding interferes with substrate recognition of ...
Marios G. Koliopoulos +10 more
doaj +1 more source
Molecular Structures of Polyglutamates
Kobunshi Kagaku, 1963 いままであまり取り上げられなかった合成ポリペプチドのポリグルタミン酸メチルの高重合体を合成し, 固体薄膜の赤外線吸収スペクトルを岩塩および臭化カリウム領城について測定した。特にα-Helix構造に基く特性吸収帯を調べるため, L型およびD型アミノ酸の各種共重合体を合成し, 吸収スペクトルを比較した。Helix構造に特有であると思われる1120, 800, 720, 620, 563cm-1の各吸収帯を見出し, これらの帰属について調べた。このうちで特に620cm-1の吸収帯はNH面外変角振動に基くアミドV吸収帯と確認され, ポリペプチド分子の空間構造の研究に有用であることがわかった。
openaire +6 more sources