Results 51 to 60 of about 12,307,698 (317)

Molecular Spectra and Molecular Structure [PDF]

open access: yesNature, 1929
THOSE who contributed to the recent Faraday Discussion on molecular spectra and molecular structure have now sent their written versions to the secretary for publication. Instead of the report we gave of Prof. Barker's explanation of the double Q branch of ammonia at 10.3 μ and 10.7 μ (NATURE, Oct. 12, p. 587), we should like to substitute Prof. Barker'
W. E. GARNER, J. E. LENNARD-JONES
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

On Atomic and Molecular Structure [PDF]

open access: yesNature, 1920
THE statement of Mr. S. C. Bradford in the second paragraph of his letter to NATURE of April 8, that I suppose the electrons to revolve in small circles without any constraining force, is erroneous. The fact that I reserved an opinion as to the nature of the constraining force does not imply, as he suggests, that I deny its existence. Thus (cf. Science
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Engineering a Pseudo-26-kDa Schistosoma Glutathione Transferase from bovis/haematobium for Structure, Kinetics, and Ligandin Studies

open access: yesBiomolecules, 2021
Glutathione transferases (GSTs) are the main detoxification enzymes in schistosomes. These parasitic enzymes tend to be upregulated during drug treatment, with Schistosoma haematobium being one of the species that mainly affect humans. There is a lack of
Neo Padi   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A machine learning model for site-specific classification of N-glycoprotein fucosylation using tandem mass spectrometry and deep neural network

open access: yesJournal of Analytical Science and Technology
Protein fucosylation is a biologically significant post-translational modification that modulates protein stability, receptor signaling, and immune function.
Mina Park, Catia Mota, Heeyoun Hwang
doaj   +1 more source

A new cellular model to follow Friedreich's ataxia development in a time-resolved way

open access: yesDisease Models & Mechanisms, 2015
Friedreich's ataxia (FRDA) is a recessive autosomal ataxia caused by reduced levels of frataxin (FXN), an essential mitochondrial protein that is highly conserved from bacteria to primates.
Tommaso Vannocci   +5 more
doaj   +1 more source

On the irregularity of some molecular structures [PDF]

open access: yesCanadian Journal of Chemistry, 2017
Measures of the irregularity of chemical graphs could be helpful for QSAR/QSPR studies and for the descriptive purposes of biological and chemical properties such as melting and boiling points, toxicity, and resistance. Here, we consider the following four established irregularity measures: the irregularity index by Albertson, the total irregularity ...
Abdo, Hosam, Dimitrov, Darko, Gao, Wei
openaire   +2 more sources

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