Results 31 to 40 of about 4,508,859 (303)

FAN1 Activity on Asymmetric Repair Intermediates Is Mediated by an Atypical Monomeric Virus-type Replication-Repair Nuclease Domain

Cell Reports, 2014
FAN1 is a structure-selective DNA repair nuclease with 5′ flap endonuclease activity, involved in the repair of interstrand DNA crosslinks. It is the only eukaryotic protein with a virus-type replication-repair nuclease (“VRR-Nuc”) “module” that commonly
Simon Pennell, Anne-Cécile Déclais, Jiejin Li, Lesley F. Haire, Wioletta Berg, José W. Saldanha, Ian A. Taylor, John Rouse, David M.J. Lilley, Stephen J. Smerdon   +9 more
doaj   +1 more source

Quasimolecular structure in elastic O16 + O16 scattering [PDF]

, 2006
It is suggested that the experimentally observed intermediate structure in the cross section of elastic O16 + O16 scattering is due to quasibound molecular states of the ion-ion system while the gross structure originates from virtually bound molecular ...
Greiner, Walter, Lemmer, Richard, Scheid, Werner   +2 more
core  

Structure determination from powder data : Mogul and CASTEP [PDF]

, 2009
When solving the crystal structure of complex molecules from powder data, accurately locating the global minimum can be challenging, particularly where the number of internal degrees of freedom is large.
Bardin, J., Florence, A. J., Griffin, T. A. N., Johnston, B., Shankland, K., Shankland, N.   +5 more
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Engineering a Pseudo-26-kDa Schistosoma Glutathione Transferase from bovis/haematobium for Structure, Kinetics, and Ligandin Studies

Biomolecules, 2021
Glutathione transferases (GSTs) are the main detoxification enzymes in schistosomes. These parasitic enzymes tend to be upregulated during drug treatment, with Schistosoma haematobium being one of the species that mainly affect humans. There is a lack of
Neo Padi, Blessing Oluebube Akumadu, Olga Faerch, Chinyere Aloke, Vanessa Meyer, Ikechukwu Achilonu   +5 more
doaj   +1 more source

Spiral shocks and the formation of molecular clouds in a two phase medium

, 2007
We extend recent numerical results (Dobbs et. al. 2006) on molecular cloud formation in spiral galaxies by including a multi-phase medium. The addition of a hot phase of gas enhances the structure in the cold gas, and significantly increases the fraction
Allen, Audit, Bate, Benz, Bergin, Blitz, Bonnell, Bonnell, C. L. Dobbs, Cox, Cox, Dobbs, Dobbs, Engargiola, Gibson, Gibson, Gittins, Glover, Glover, Heitsch, Heyer, I. A. Bonnell, Kaufman, Kim, Kim, Klaassen, Le Petit, Lequeux, Mac Low, Monaghan, Monaghan, Ostriker, Piontek, Pringle, Solomon, Thacker, Vazquez-Semadeni, Vazquez-Semadeni, Vogel, Wada, Wada, Wada, Williams, Williams, Wolfire   +44 more
core   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Identification of RING E3 pseudoligases in the TRIM protein family

Nature Communications
TRIpartite Motif (TRIM) family proteins have diverse roles across a broad variety of cellular functions, which are largely presumed to depend on their ubiquitin E3 ligase activity, conferred by a RING domain.
Jane Dudley-Fraser, Diego Esposito, Katherine A. McPhie, Coltrane Morley-Williams, Tania Auchynnikava, Katrin Rittinger   +5 more
doaj   +1 more source

Do we need to know the temperature in prestellar cores?

, 2007
Molecular line observations of starless (prestellar) cores combined with a chemical evolution modeling and radiative transfer calculations are a powerful tool to study the earliest stages of star formation. However, conclusions drawn from such a modeling
Henning, Th., Pavlyuchenkov, Ya., Wiebe, D.   +2 more
core   +1 more source

Uncertainty Estimates for Theoretical Atomic and Molecular Data [PDF]

, 2016
Sources of uncertainty are reviewed for calculated atomic and molecular data that are important for plasma modeling: atomic and molecular structure and cross sections for electron-atom, electron-molecule, and heavy particle collisions.
Bartschat, K., Braams, B. J., Chung, H. -K., Csaszar, A. G., Drake, G. W. F., Kirchner, T., Kokoouline, V., Tennyson, J.   +7 more
core   +2 more sources