Results 31 to 40 of about 5,797,712 (321)

Mathematical model of a serine integrase-controlled toggle switch with a single input [PDF]

, 2018
Dual-state genetic switches that can change their state in response to input signals can be used in synthetic biology to encode memory and control gene expression.
Colloms, Sean D., Ebenhöh, Oliver, Pokhilko, Alexandra, Stark, W. Marshall   +3 more
core   +1 more source

A Molecular Platinum Cluster Junction: A Single-Molecule Switch [PDF]

, 2013
We present a theoretical study of the electronic transport through single-molecule junctions incorporating a Pt6 metal cluster bound within an organic framework.
Barraza-Lopez S., Bergfield J. P., Boardman B. M., Bokdam M., Cuevas J. C., de Biani F. F., Edmund Leary, Femoni C., Finch C. M., García-Lastra J. M., Georgiev V. P., Gerasimov Y. S., Gerasimov Y. S., Gubin S. P., Guedon C. M., Haiss W., Heersche H. B., Isomura N., Juan Carlos Cuevas, Juan Jose Palacios, Kaliginedi V., Leary E., Leary E., Leary E., Linda A. Zotti, Maria Soriano, Markussen T., Mayor M., Meded V., Nichols R. J., Park H., Park J., Renani F. R., Ruben M., Satanin A. M., Soldatov E. S., Wei Z., Yasumatsu H., Zhang J.   +38 more
core   +2 more sources

Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis

Nature Communications, 2018
Aggregation is sequence-specific and nucleated by short aggregating protein segments (APR). Here authors use a multidisciplinary approach to show that in E.coli some frequently occurring APRs lead to protein aggregation and ultimately bacterial cell ...
Ladan Khodaparast, Laleh Khodaparast, Rodrigo Gallardo, Nikolaos N. Louros, Emiel Michiels, Reshmi Ramakrishnan, Meine Ramakers, Filip Claes, Lydia Young, Mohammad Shahrooei, Hannah Wilkinson, Matyas Desager, Wubishet Mengistu Tadesse, K. Peter R. Nilsson, Per Hammarström, Abram Aertsen, Sebastien Carpentier, Johan Van Eldere, Frederic Rousseau, Joost Schymkowitz   +19 more
doaj   +1 more source

Dual Modulation of Single Molecule Conductance via Tuning Side Chains and Electric Field with Conjugated Molecules Entailing Intramolecular O•••S Interactions

Advanced Science, 2022
Herein, single‐molecule conductance studies of TBT1‐TBT6 which entails 1,4‐dithienylbenzene as the backbone and SMe groups as the anchoring units, with the scanning tunneling microscope break junction (STM‐BJ) technique, are reported.
Hua Zhang, Wei Xu, Kai Song, Taige Lu, Guanxin Zhang, Yaping Zang, Wenjing Hong, Deqing Zhang   +7 more
doaj   +1 more source

Silicon-based molecular switch junctions [PDF]

, 2009
In contrast to the static operations of conventional semiconductor devices, the dynamic conformational freedom in molecular devices opens up the possibility of using molecules as new types of devices such as a molecular conformational switch or for ...
Cuniberti, Gianaurelio, Nozaki, Daijiro
core   +2 more sources

A Novel Molecular Switch [PDF]

Journal of Molecular Biology, 2009
Transcriptional regulation is a fundamental process for regulating the flux of all metabolic pathways. For the last several decades, the lac operon has served as a valuable model for studying transcription. More recently, the switch that controls the operon has also been successfully adapted to function in mammalian cells.
Robert, Daber, Mitchell, Lewis
openaire   +2 more sources

Resonant Electron Tunneling Induces Isomerization of π‐Expanded Oligothiophene Macrocycles in a 2D Crystal

Advanced Science, 2022
Macrocyclic oligothiophenes and their π‐expanded derivatives constitute versatile building blocks for the design of (supra)molecularly engineered active interfaces, owing to their structural, chemical, and optoelectronic properties.
José D. Cojal González, Masahiko Iyoda, Jürgen P. Rabe   +2 more
doaj   +1 more source

One Scaffold, Two Conformations: The Ring-Flip of the Messenger InsP₈ Occurs under Cytosolic Conditions

Biomolecules, 2023
Inositol poly- and pyrophosphates (InsPs and PP-InsPs) are central eukaryotic messengers. These very highly phosphorylated molecules can exist in two distinct conformations, a canonical one with five phosphoryl groups in equatorial positions, and a ...
Leonie Kurz, Peter Schmieder, Nicolás Veiga, Dorothea Fiedler   +3 more
doaj   +1 more source

Molecular switches at surfaces [PDF]

Journal of Physics: Condensed Matter, 2012
In nature, molecules exploit interaction with their environment to realize complex functionalities on the nanometer length scale. Physical, chemical and/or biological specificity is frequently achieved by the switching of molecules between microscopically different states.
Weinelt, Martin, Oppen, Felix
openaire   +2 more sources

A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection

Nature Communications, 2019
Class F receptors are considered valuable therapeutic targets due to their role in human disease, but structural changes accompanying receptor activation remain unexplored.
Shane C. Wright, P. Kozielewicz, Maria Kowalski-Jahn, J. Petersen, Carl-Fredrik Bowin, Greg Slodkowicz, M. Marti-Solano, D. Rodríguez, B. Hot, Najeah Okashah, Kateřina Straková, Jana Valnohova, M. M. Babu, N. Lambert, Jens Carlsson, G. Schulte   +15 more
semanticscholar   +1 more source