Results 61 to 70 of about 5,964,508 (225)
New molecular switch architectures [PDF]
Proceedings of the National Academy of Sciences, 2018 In this paper we elaborate on recently developed molecular switch architectures and how these new systems can help with the realization of new functions and advancement of artificial molecular machines. Progress in chemically and photoinduced switches and motors is summarized and contextualized such that the reader may gain an appreciation for the ...
Jared D, Harris +2 more
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Detection of Side Chain Rearrangements Mediating the Motions of Transmembrane Helices in Molecular Dynamics Simulations of G Protein-Coupled Receptors. [PDF]
, 2017 Structure and dynamics are essential elements of protein function. Protein structure is constantly fluctuating and undergoing conformational changes, which are captured by molecular dynamics (MD) simulations.
Gaieb, Zied, Morikis, Dimitrios
core +2 more sources
Cysteines as Redox Molecular Switches and Targets of Disease
Frontiers in Molecular Neuroscience, 2017 Thiol groups can undergo numerous modifications, making cysteine a unique molecular switch. Cysteine plays structural and regulatory roles as part of proteins or glutathione, contributing to maintain redox homeostasis and regulate signaling within and ...
A. Fra, E. Yoboue, R. Sitia
semanticscholar +1 more source
Molecular switch of EZH2 in hypoxia [PDF]
Cell Cycle, 2016 Over the past decades, several reports on a non-canonical function of Ezh2 and discoveries of its novel partners, other than its canonical PRC2 members i.e.
Sylvia, Mahara, Wee Joo, Chng, Qiang, Yu
openaire +2 more sources
Thermodynamics and Kinetics of Guest-Induced Switching between “Basket Handle” Porphyrin Isomers
Molecules, 2014 The synthesis and switching properties of two “basket handle” porphyrin isomers is described. The cis-oriented meso-phenyl groups of these porphyrins are linked at their ortho-positons via benzocrown-ether-based spacers, which as a result of slow ...
Alexander B. C. Deutman +6 more
doaj +1 more source
Beyond the fuzzy lock-and-key: spontaneous symmetry shifts and glycan/lectin logic gates [PDF]
, 2012 Changes in the molecular topology of glycan/lectin interaction may explain observed reaction punctuation driven by experimental gradients in reactant concentration. Adoption of a 'biological renormalization' perspective from statistical physics
Rodrick Wallace
core +1 more source
Src as the link between inflammation and cancer. [PDF]
, 2013 Although a causal link between chronic inflammation and cancer has been established, the exact molecular mechanism linking inflammation to cancer remains largely unknown.
Andrzej ePtasznik +4 more
core +2 more sources
Radically Enhanced Molecular Switches [PDF]
Journal of the American Chemical Society, 2012 The mechanism governing the redox-stimulated switching behavior of a tristable [2]rotaxane consisting of a cyclobis(paraquat-p-phenylene) (CBPQT(4+)) ring encircling a dumbbell, containing tetrathiafulvalene (TTF) and 1,5-dioxynaphthalene (DNP) recognition units which are separated from each other along a polyether chain carrying 2,6-diisopropylphenyl ...
Fahrenbach, Albert C. +10 more
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A modular and extensible RNA-based gene-regulatory platform for engineering cellular function [PDF]
, 2007 Engineered biological systems hold promise in addressing pressing human needs in chemical processing, energy production, materials construction, and maintenance and enhancement of human health and the environment. However, significant advancements in our
Smolke, Christina D., Win, Maung Nyan
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Molecular dynamics simulations of oxide memory resistors (memristors)
, 2010 Reversible bipolar nano-switches that can be set and read electronically in a solid-state two-terminal device are very promising for applications. We have performed molecular-dynamics simulations that mimic systems with oxygen vacancies interacting via ...
A M Bratkovsky +16 more
core +1 more source