Results 81 to 90 of about 3,557,904 (289)
meta-Oligoazobiphenyls – synthesis via site-selective Mills reaction and photochemical properties
Beilstein Journal of Organic Chemistry, 2012 The investigation of multi-photochromic compounds constitutes a great challenge, not only from a synthetic point of view, but also with respect to the analysis of the photochemical properties.
Raphael Reuter, Hermann A. Wegner
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Carbon FutureMolecular switches are widely studied in optical devices, computer science, DNA sensor systems, and chiral synthesis; however, their use in heterogeneous catalytic processes is rarely reported.
Qiongfang Hu +3 more
doaj +1 more source
On the bromination of the dihydroazulene/vinylheptafulvene photo-/thermoswitch
Beilstein Journal of Organic Chemistry, 2012 Background: The dihydroazulene (DHA)/vinylheptafulvene (VHF) system (with two cyano groups at C1) functions as a photo-/thermoswitch. Direct ionic bromination of DHA has previously furnished a regioselective route to a 7,8-dibromide, which by elimination
Virginia Mazzanti +6 more
doaj +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Charge transport through molecular switches
, 2010 We review the fascinating research on charge transport through switchable molecules. In the past decade, detailed investigations have been performed on a great variety of molecular switches, including mechanically interlocked switches (rotaxanes and ...
Molen, S.J. +5 more
core +1 more source
Recent advances towards azobenzene-based light-driven real-time information-transmitting materials
Beilstein Journal of Organic Chemistry, 2012 Photochromic switches that are able to transmit information in a quick fashion have attracted a growing interest within materials science during the last few decades.
Jaume García-Amorós, Dolores Velasco
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Nanoparticles functionalised with reversible molecular and supramolecular switches
, 2010 Nanoparticles (NPs) and molecular/supramolecular switches have attracted considerable interest during the past decade on account of their unique properties and prominent roles in the fields of organic chemistry and materials science.
Stoddart, J. Fraser +5 more
core +1 more source