Results 181 to 190 of about 2,123,606 (402)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

The SGK3-Catalase antioxidant signaling axis drives cervical cancer growth and therapy resistance

open access: yesRedox Biology, 2023
Cancer cells frequently exhibit aberrant redox homeostasis and adaptation to oxidative stress. Hence abrogation of redox adaptation in cancer cells can be exploited for therapeutic benefit.
Min Wang   +7 more
doaj  

Molecular targeted therapy for metastatic colorectal cancer: current and evolving approaches. [PDF]

open access: yesFront Pharmacol, 2023
Li F   +12 more
europepmc   +1 more source

Quantification of molecular and anatomical target contours of head and neck cancer to facilitate image-guided therapy during IMRT [PDF]

open access: bronze, 2003
Christopher Scarfone   +6 more
openalex   +1 more source

Sarcoma: Molecular-Targeted Therapies

open access: yesAnnals of Oncology, 2012
ABSTRACT Sarcomas are rare heterogeneous malignant neoplasms that arise from mesenchymal tissues and are clinically divided into two main categories, that is, bone and soft tissue sarcomas. The overall frequency of sarcomas is ∼1% of all adult solid malignancies, and the incidence of bone sarcomas and soft-tissue sarcomas is estimated to be four ...
openaire   +2 more sources

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

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