Results 141 to 150 of about 1,370,451 (310)

Diagnosis of protozoa diarrhoea in Campylobacter patients increases markedly with molecular techniques. [PDF]

PLOS Glob Public Health, 2023
Hayman DTS, Garcia-Ramirez JC, Pita A, Velathanthiri N, Knox MA, Ogbuigwe P, Baker MG, Rostami K, Deroles-Main J, Gilpin BJ.   +9 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Chorionic Villus Sampling in the Era of Genomic Medicine: A Gateway to Early and Personalized Prenatal Diagnosis

The Application of Clinical Genetics
Urszula Wysocka,1 Jolanta Stępniewska,1 Magdalena Kozłowska,1 Agata Kucińska,1 Patrycja Banaś-Leżańska,1 Wojciech Ałaszewski,1 Lech Dudarewicz,1 Piotr Kaczmarek,2 Mariusz Stanis ...
Wysocka U, Stępniewska J, Kozłowska M, Kucińska A, Banaś-Leżańska P, Ałaszewski W, Dudarewicz L, Kaczmarek P, Grzesiak MS, Gach A   +9 more
doaj  

Leucocytozoon infections in tits (Aves, Paridae): blood and tissue stages investigated using an integrative approach

Parasite
Leucocytozoon species are cosmopolitan and prevalent avian parasites, with some infections being lethal, mainly due to the exo-erythrocytic development of the parasite in bird tissues.
Gutiérrez-Liberato Germán Alfredo, Duc Mélanie, Eigirdas Vytautas, Chagas Carolina Romeiro Fernandes   +3 more
doaj   +1 more source

Validation of the efficacy of air purifiers using molecular techniques. [PDF]

PLoS One, 2023
Rausch F, Tanneberger F, Abd El Wahed A, Truyen U.   +3 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Molecular Techniques (2015-2016). Protocol for the Genetics Laboratory practices

, 2016
Protocol for the Genetics Laboratory ...
Salinas, Paloma
core  

Molecular techniques drive cutting edge advancements in management of cutaneous T cell lymphoma. [PDF]

Front Immunol, 2023
Lefebvre MN, Borcherding N, Reis RJ, Mou E, Liu V, Jabbari A.   +5 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Modelling abrasive machining techniques using molecular dynamics

, 2008
The development of ultra–precision processes which can achieve nanometre surface finishes and tolerances is now a critical requirement for many applications in medical, electronics and energy industry.
Oluwajobi, Akinjide O., Chen, Xun
core