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Molecular similarity: a key technique in molecular informatics

Organic & Biomolecular Chemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Andreas, Bender, Robert C, Glen
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Molecular techniques in transplantation

Transplantation Proceedings, 2004
Molecular tools may prove useful for diagnosis, monitoring, and definition of basic mechanisms in transplantation. These techniques must be quantitative, reproducible and rapid, displaying known sensitivity and specificity. Powerful new techniques with "real-time" application, as briefly reviewed herein, are moving closer to clinical utility.
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Microbial Molecular Techniques

2001
Abstract An avalanche of new molecular typing tests has recently overwhelmed hospital epidemiologists, field epidemiologists, and infectious disease clinicians. The plethora of new acronyms confuse even experts in the field, many of whom have given up following each development unless it is related to their own research.
Loreen A Herwaldt   +2 more
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Molecular biology techniques

2022
This chapter examines molecular biology, which is generally concerned with the structures, functions, and interactions of the two major groups of macromolecules, the nucleic acids DNA and RNA, and proteins. Nucleic acids can be purified from organisms using a variety of techniques.
Qiuyu Wang, Nessar Ahmed, Chris Smith
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Basic Molecular Biology Techniques

2003
Molecular biology was first referred to as the study of the chemical and physical structure of biological macromolecules such as nucleic acids and proteins. Nucleic acids, deoxyribonucleic acid (DNA), and ribonucleic acid (RNA) are polymers that consist of nucleotides. Proteins are polymers that consist of several amino acids.
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Molecular Neurobiological Techniques

1989
Analysis of Brain mRNAs by Translation in Vitro.- Preparation of cDNA Libraries and Isolation and Analysis of Specific Clones.- Preparation and Use of Subtractive cDNA Hybridization Probes for cDNA Cloning.- Analysis of Brain-Specific Gene Products.- Isolation and Structure Determination of Genes.- Gene-Mapping Techniques.- Methods for Genetic Linkage ...
Alan A. Boulton   +2 more
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Molecular Biology Techniques

2021
The development of vast array of laboratory methods and their applications provided great leaps in the ability of the researchers to discover new features and functions of macro-molecules. Most of them represent procedures for measuring or visualizing ever-smaller quantities or tinier features of molecules, or part of molecules. Especially when applied
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Molecular Ancillary Techniques

2013
In the setting of ambiguous melanocytic proliferations, the utility of ancillary molecular techniques is still controversial. Currently ancillary techniques such as comparative genomic hybridization and fluorescence in situ hybridization cannot replace conventional microscopy.
Mai P. Hoang   +2 more
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Molecular techniques in Whipple’s disease

Expert Review of Molecular Diagnostics, 2001
Whipple's disease is a systemic infection, caused by the bacterium Tropheryma whipplei, with protean clinical manifestations characterized by fever, weight loss, diarrhea, polyarthritis, skin hyperpigmentation and adenopathy. For a long time, due to the inability to culture the causative organism, diagnosis was based on histologic examination of ...
F, Fenollar, D, Raoult
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Molecular Microecological Techniques

2014
Recent researches have shown that microbes associated with the human body are approximately 10 times more numerous than our own cells and contain, in aggregate, about 100 times more genes. This has led to the viewpoint that humans and our microbial symbionts should be considered as “superorganisms”.
Zongxin Ling, Charlie Xiang
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