Results 81 to 90 of about 2,569,624 (298)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Green function techniques in the treatment of quantum transport at the molecular scale

, 2008
The theoretical investigation of charge (and spin) transport at nanometer length scales requires the use of advanced and powerful techniques able to deal with the dynamical properties of the relevant physical systems, to explicitly include out-of ...
A. Aviram, A. Bannani, A. Carlo Di, A. Ferretti, A. Gagliardi, A. Mitra, A. Mitra, A. Nitzan, A. Pecchia, A. Pecchia, A. Pecchia, A. Pecchia, A. Thielmann, A. Thielmann, A. Zazunov, A. Zazunov, A. Zazunov, A.C. Hewson, A.C. Johnson, A.D. Stone, A.P. Jauho, A.P. Jauho, A.R. Rocha, A.S. Alexandrov, A.Y. Smirnov, B. Muralidharan, B. Muralidharan, B. Song, B. Xu, B.C. Stipe, B.N.J. Persson, B.R. Bulka, B.Y. Choi, C. Caroli, C. Caroli, C. Caroli, C. Joachim, C. Joachim, C. Lacroix, C. Niu, C. Niu, C. Timm, C.B. Duke, C.R. Treadway, C.W.J. Beenakker, D. Boese, D. Fedorets, D. Fedorets, D. Fedorets, D. Mozyrsky, D. Porath, D. Porath, D. Porath, D.A. Ryndyk, D.A. Ryndyk, D.A. Ryndyk, D.A. Ryndyk, D.K. Ferry, D.S. Fisher, D.V. Averin, D.V. Averin, D.V. Averin, D.V. Averin, E. Bonet, E. Lörtscher, E. Meggers, E. Runge, E. Shapir, E.A. Osorio, E.G. Petrov, E.G. Petrov, E.G. Petrov, E.N. Economou, F. Aryasetiawany, F. Elste, F. Pump, F.E. Olsson, G. Baym, G. Baym, G. Begemann, G. Caliskan, G. Cuniberti, G. Cuniberti, G. Fagas, G. Mahan, G. Onida, G.V. Nazin, H. Bruus, H. M. Pastawski, H. M. Pastawski, H. Park, H. Raza, H. Schoeller, H.M. Pastawski, H.P. Breuer, H.U. Baranger, I.G. Lang, J. Aghassi, J. Bardeen, J. Chen, J. Hubbard, J. Hubbard, J. Hubbard, J. Inarrea, J. Koch, J. Koch, J. Koch, J. Kushmerick, J. König, J. König, J. König, J. König, J. L. D’Amato, J. Park, J. Rammer, J. Repp, J. Repp, J. Repp, J. Richter, J. Taylor, J. Taylor, J. Taylor, J. Tersoff, J. Tersoff, J. von Delft, J.C. Charlier, J.J. Palacios, J.N. Pedersen, J.R. Hahn, J.X. Zhu, K. Flensberg, K. Huang, K. Keren, K. Ono, K.D. McCarthy, K.S. Thygesen, K.S. Thygesen, K.S. Thygesen, L. E. F. Foa Torres, L. Hedin, L. Kadanoff, L. Mayrhofer, L. Venkataraman, L. Yi, L.H. Yu, L.H. Yu, L.I. Glazman, L.I. Glazman, L.V. Keldysh, L.Y. Gorelik, M. Albrecht, M. Brandbyge, M. Büttiker, M. Büttiker, M. Büttiker, M. Cízek, M. Cízek, M. Elbing, M. Galperin, M. Galperin, M. Galperin, M. Galperin, M. Galperin, M. Galperin, M. Grifoni, M. Jonson, M. Martin, M. Mertig, M. Paulsson, M. Paulsson, M. Paulsson, M. Plihal, M. Poot, M. R. Wegewijs, M. Sigrist, M. Sigrist, M. Valle del, M. Ventra Di, M.A. Gata, M.A. Ratner, M.A. Reed, M.A. Reed, M.H. Cohen, M.H. Hettler, N. Liu, N. Nilius, N. Nilius, N. Sai, N. Sergueev, N.A. Pradhan, N.M. Chtchelkatchev, N.S. Wingreen, N.S. Wingreen, N.S. Wingreen, N.S. Wingreen, P. Ao, P. Delaney, P. Delaney, P. D’Amico, P. Král, P. Liljeroth, P. Pals, P. R. Levstein, P.C. Martin, P.I. Arseyev, P.I. Arseyev, P.S. Damle, P.W. Anderson, R. Aguado, R. Combescot, R. Gutierrez, R. Gutierrez, R. Gutierrez, R. Gutiérrez, R. Landauer, R. Landauer, R. Landauer, R. Liu, R. Sanchez, R. Schleser, R. Swirkowicz, R.E. Prange, R.H.M. Smit, S. Braig, S. Datta, S. Datta, S. Datta, S. Hershfield, S. Kohler, S. Kurth, S. Lamba, S. Sanvito, S. Tikhodeev, S. Tikhodeev, S.H. Ke, S.H. Ke, S.H. Ke, S.H. Ke, S.H. Ke, S.O. Kelley, S.W. Hla, S.W. Wu, S.W. Wu, T. Frederiksen, T. Frederiksen, T. Frederiksen, T. Fujii, T. Holstein, T. Mii, T. Mii, T. Novotný, T. Novotný, T. Rakshit, T.K. Ng, T.N. Todorov, T.S. Kim, Th. Frauenheim, U. Harbola, U. Lundin, V.I. Anisimov, W. Ho, W. Liang, W.A. Harrison, W.G. Wiel van der, W.J.M. Naber, X. Wang, X. Xiao, X.H. Qiu, Y. Ke, Y. Kim, Y. Meir, Y. Meir, Y. Meir, Y. Xue, Y. Xue, Y. Xue, Y. Xue, Y.J. Lee, Ya. M. Blanter, Z. Ning   +279 more
core   +2 more sources

Fungal-Infected Weeds: A Potential Source of Leaf Spot Disease in Rubber Trees from Southern Thailand

Journal of Fungi
The rubber tree (Hevea brasiliensis) is an economically important crop in Thailand. Severe defoliation caused by emerging diseases has been reported to substantially reduce rubber yields during the leaf fall phase.
Narit Thaochan, Chaninun Pornsuriya, Thanunchanok Chairin, Kodeeyah Thoawan, Putarak Chomnunti, Anurag Sunpapao   +5 more
doaj   +1 more source

Molecular techniques for the study and diagnosis of parasite infection

Journal of Venomous Animals and Toxins including Tropical Diseases, 2011
In parasitology, routine laboratory diagnosis involves conventional methods, such as optical microscopy, used for the morphological identification of parasites. Currently, molecular biology techniques are increasingly used to diagnose parasite structures
RG Tavares, R Staggemeier, ALP Borges, MT Rodrigues, LA Castelan, J Vasconcelos, ME Anschau, SM Spalding   +7 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Detection Limit for Optically Sensing Specific Protein Interactions in Free-solution

, 2017
Optical molecular sensing techniques are often limited by the refractive index change associated with the probed interactions. In this work, we present a closed form analytical model to estimate the magnitude of optical refractive index change arising ...
Sasikumar, Harish, Varma, Manoj M.
core   +1 more source

A Review of the Classical and Molecular Diagnostic Methods of Herpes Simplex Virus

Bihdād, 2020
Human Herpes Viruses (HSV) contain eight pathogens. HSV is one of the most widespread viruses in the world and due to the simplicity of the way of transmission the number of people infected with the virus has increased in per year.
Aref Atefi, Parisa Dehghan, Amir Hossien Ahmadieh Yazdi, Anahita Khosravi   +3 more
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source