Results 91 to 100 of about 1,603,639 (321)

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Amount of TNF-α released from macrophages reacting with polyethylene particles showed dose-dependent relationship to the total surface area of added particles

open access: yesBiosurface and Biotribology, 2018
The immune response to ultra-high molecular weight polyethylene wear debris is thought to be one of the major causes of osteolysis and aseptic loosening.
Weiqi Shen   +3 more
doaj   +1 more source

Bimodal molecular mass distribution in surfactant-free emulsion polymerization as a consequence of coagulative nucleation [PDF]

open access: yesarXiv, 2017
It is demonstrated that the often observed broadness of the molecular weight distribution obtained from latex particles synthesized by means of surfactant-free emulsion polymerization results from the multistage kinetics. The initial stage of the polymerization, by which the primary particles are formed, is of the 01-kind which means that it can be ...
arxiv  

Molecular Weight of Malt-Amylase [PDF]

open access: yesNature, 1948
IN an earlier investigation1, the molecular weight of α-amylase from pig‘s pancreas2,3 Was found to be 45,000, as calculated from the values4 s20 = 4·50 S, D = 8·05 × 10-7 C.G.S. and V20 = 0·70. At this Institute a new method for the isolation of amylase from malt has been developed5.
openaire   +3 more sources

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

The Molecular Weight and Aggregation of DNA

open access: yesBiophysical Journal, 1961
The effects of enzymatic attack and of shear during the isolation and deproteinization of DNA have been investigated. Different methods of disaggregating DNA have been studied, and conditions under which reaggregation can occur are discussed. It was found that shaking with chloroform-octanol does not degrade DNA from the seven sources studied; that ...
Liebe F. Cavalieri   +2 more
openaire   +3 more sources

Birch Wood Constituents. I. Carbohydrates of Low Molecular Weight. [PDF]

open access: bronze, 1958
Bengt Lindberg   +5 more
openalex   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

The Constituents of Conifer Needles. I. Low Molecular Weight Carbohydrates in the Needles of Pinus silvestris. [PDF]

open access: bronze, 1958
Anders P. Assarsson   +5 more
openalex   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

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