Results 251 to 260 of about 1,582,362 (287)

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic   +6 more
wiley   +1 more source

On the molecular weight of myosin

Biochimica et Biophysica Acta, 1958
Abstract By the Archibald approach to sedmentation equilibrium method, we have found a molecular weight of 4.2·10 5 g for either, (I) myosin (A) or, (2) the principal, ( ca . 65% by weight), schlieren-visible component of 5-h extracted myosin B. This same value has also been estimated from the conventional sedimentation velocity-diffusion method ...
P H, VON HIPPEL   +3 more
openaire   +2 more sources

Molecular Weight Determinations

Science, 1961
A Beams magnetically suspended equilibrium ultracentrifuge was used to determine the molecular weight of sucrose, ribonuclease, and insulin. Both long- and short-column ultracentifuge cells were used. The longer cells gave greater precision, but required a longer time for equilibrium to occur.
R D, Boyle, P E, Hexner
openaire   +2 more sources

Whale High-Molecular-Weight and Low-Molecular-Weight Kininogens

Thrombosis Research, 2000
The expression of high-molecular-weight and low-molecular-weight kininogen mRNAs in the whale liver was examined by reverse transcription-polymerase chain reaction. The nucleotide sequences of the high-molecular-weight and low-molecular-weight kininogen cDNAs were analyzed and deduced to the amino acid sequences.
U, Semba   +4 more
openaire   +2 more sources

Molecular Weights and Molecular-Weight Distributions

1977
In synthesizing macromolecules in vitro and in vivo, monodisperse macromolecules (i.e., those in which every molecule has the same molecular weight) only occur under specific mechanistic conditions. The overwhelming majority of reactions proceed more or less randomly, and the resulting macromolecular substance shows a more or less broad molecular ...
openaire   +1 more source

Molecular Weight and Molecular Weight Distribution of Kraft Lignins

MRS Proceedings, 1990
ABSTRACTKraft lignins are the lignin degradation products from kraft pulping. They are complex, heterogeneous polymers with some polar character. The molecular weight of kraft lignins greatly affect the physical properties of black liquors, and are of primary importance in separation from black liquor and in evaluating potential uses.Several purified ...
Wolfgang Schmidl   +2 more
openaire   +1 more source

Molecular Weights of Enzymes

Nature, 1962
IN a recent article Wright1 put forward the hypothesis that the molecular weights of the enzymes tabulated by Dixon and Webb2 fall near three series of numbers expressed by 2n × 12,000, 2n × 16,000 and 2n × 19,000, n taking integral values 0–4. This hypothesis was based entirely on the experimental values themselves, mainly by means of graphical ...
openaire   +2 more sources

Determination of Molecular Weight and Molecular-Weight Distribution

1977
Molecular-weight determination methods can be classed as absolute, equivalent, or relative. Absolute methods allow the molecular weight to be calculated directly from the measured quantities; a knowledge of the physical and chemical structure of the molecules is not required.
openaire   +1 more source

Home - About - Disclaimer - Privacy