Results 261 to 270 of about 1,609,811 (321)

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden, Charles Carron, Donatienne Van Weehaeghe, Joke De Vocht, Fouke Ombelet, Pegah Masrori, Caro De Weerdt, Rebecca E. James, Lauren T. Evans, Frederick A. Schroeder, Jacob M. Hooker, Michel Koole, Janice E. Kranz, Tonya M. Gilbert, Philip Van Damme, Koen Van Laere   +15 more
wiley   +1 more source

Calcium Phosphate Nanoparticles as Carriers of Low and High Molecular Weight Compounds. [PDF]

Int J Mol Sci
Popova E, Tikhomirova V, Akhmetova A, Ilina I, Kalinina N, Taliansky M, Kost O.   +6 more
europepmc   +1 more source

Determination of Molecular Weights in the Vapor State from Vapor Pressure and Evaporation Data (Washburn, E. W.)

, 1929
Mildred W. Grafflin
openalex   +1 more source

Pregnancy Outcomes of Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Among Patients With Autoimmune Diseases: A Scoping Review

Arthritis Care &Research, EarlyView.
Objective Targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) have expanded the management of autoimmune diseases, including rheumatic diseases. As the use of these drugs grows, it is important to understand their effects on pregnancy.
Vienna Cheng, Neda Amiri, Vicki Cheng, Ursula Ellis, Jacquelyn J. Cragg, Mark Harrison, Laurie Proulx, Mary A. De Vera   +7 more
wiley   +1 more source

Size-dependent aggregation of erythrocytes by low molecular weight hyaluronic acids of different sizes: bioactivity and quality control potential. [PDF]

Front Physiol
Ma X, Wang X, Jia X, Hui JH, Shofaro JH, Tao R, Hui MM.   +6 more
europepmc   +1 more source

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

Advanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard, Kaja Borup Løvschall, Mireia Casanovas Montasell, Clara Bakkegaard Cramer, Pere Monge Marcet, Andreas Bøtker Pedersen, Josefine Hammer Jakobsen, Alexander N. Zelikin   +7 more
wiley   +1 more source

Discovery of selective low molecular weight interleukin-36 receptor antagonists by encoded library technologies. [PDF]

Nat Commun
Velcicky J, Cremosnik G, Scheufler C, Meier P, Wirth E, Felber R, Ramage P, Schaefer M, Kaiser C, Lehmann S, Kutil R, Singeisen S, Mueller-Ristig D, Popp S, Cebe R, Lehr P, Kaupmann K, Erbel P, Röhn TA, Giovannoni J, Dumelin CE, Martiny-Baron G.   +21 more
europepmc   +1 more source

Effects of Dalcroze Eurhythmics Exercise Versus Multicomponent Exercise on Physical and Cognitive Function, and Falls in Older Adults: The EPHYCOS Randomized Controlled Trial

Advanced Biology, EarlyView.
In this randomized clinical trial conducted among 142 community‐dwelling older adults at high risk for falls over 12 months, a Dalcroze Eurhythmics exercise intervention (once weekly, group‐based) improved a variety of physical and cognitive/executive function outcomes compared with a multicomponent exercise intervention (twice weekly, group‐ and home ...
Mélany Hars, Natalia Fernandez, François Herrmann, René Rizzoli, Serge Ferrari, Christophe Graf, Patrik Vuilleumier, Andrea Trombetti   +7 more
wiley   +1 more source

Protein profile of spermatozoa and seminal plasma based on molecular weight in four phenotypes of <i>Kokok Balenggek</i> roosters. [PDF]

Open Vet J
Jaswandi J, Rusfidra R, Ananda A, Abimanyu AA, Gusdinal H.   +4 more
europepmc   +1 more source

Characterization and Optimization of Vesicle Properties in bioPISA: from Size Distribution to Post‐Assembly Loading

Advanced Biology, EarlyView.
The paper explores the creation and characterization of vesicles through biocatalytic Polymerization‐Induced Self‐Assembly (bioPISA), focusing on achieving size uniformity using centrifugation techniques. It examines the effects of stirring speed on vesicle morphology and analyses the internal polymer‐rich structure using fluorescence correlation ...
Andrea Belluati, Adrian Bloch, Kaloian Koynov, Mariana Müller Nieva, Mohadeseh Bagherabadi, Annette Andrieu‐Brunsen, Harald Kolmar, Nico Bruns   +7 more
wiley   +1 more source