Results 61 to 70 of about 3,015,620 (304)

Molecular Weight of Urokinase [PDF]

Nature, 1965
UROKINASE is a proteolytic enzyme in human urine1. Its ability to activate plasminogen has stimulated interest in its potential clinical use as a thrombolytic agent.
R A, Burges, K W, Brammer, J D, Coombes
openaire   +2 more sources

Size-tuneable nanometric MRI contrast agents for the imaging of molecular weight dependent transport processes [PDF]

, 2014
Purpose: To evaluate size-tuneable nanomeric glycol-chitosan-DTPA-Gd conjugates as MRI contrast agents for the imaging of molecular weight (MW) dependent transport processes.
Condon, Barrie, Dufes, Christine, Holmes, William M., MacLellan, Steven, Mazen, Mazen M., Schätzlein, Andreas G., Uchegbu, Ijeoma F.   +6 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Preparation and characterization of low-molecular-weight heparin/protamine nanoparticles (LMW-H/P NPs) as FGF-2 carrier

International Journal of Nanomedicine, 2010
Yasutaka Mori1,3,4, Shingo Nakamura2, Satoko Kishimoto1, Mitsuyuki Kawakami4, Satoshi Suzuki4, Takemi Matsui4, Masayuki Ishihara11Research Institute, 2Department of Surgery, National Defense Medical College, Tokorozawa, Saitama, Japan; 3Aeromedical ...
Yasutaka Mori, Shingo Nakamura, Satoko Kishimoto, et al   +3 more
doaj  

Phase separation effects and the nematic-isotropic transition in polymer and low molecular weight liquid crystals doped with nanoparticles [PDF]

, 2013
Properties of the nematic–isotropic phase transition in polymer and low molecular weight liquid crystals doped with nanoparticles have been studied both experimentally and theoretically in terms of molecular mean-field theory.
Alexey S. Merekalov, Alina M. Shatalova, Anderson, Barmatov, Bellini, Buchnev, Duran, Georgiy A. Shandryuk, Gorkunov, Humphries, Irina Yu. Kutergina, Kaur, Kobayashi, Kopcansky, Kopcanskya, Kumar, Li, Li, Lifshitz, Lopatina, Matsuyama, Matsuyama, Maxim V. Gorkunov, Merekalov, Mikhail A. Osipov, Milette, Milette, Peterson, Qi, Qi, Qi, Raisa V. Talroze, Reznikov, Shandryuk, Shandryuk, Shatalova, Shiraishi, Sinha, Tselikov, Vecchi, Wang, Wiegeleben, Yamamoto, Yaroslav V. Kudryavtsev, Yoshida, Yoshida   +45 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes [PDF]

, 1986
Several cDNA clones coding for the high molecular weight (alpha) subunit of the voltage-sensitive Na channel have been selected by immunoscreening a rat brain cDNA library constructed in the expression vector lambda gt11.
Auld, Vanessa, Catterall, William A., Davidson, Norman, Downey, William, Dowsett, Andrew, Dunn, Robert, Fritz, Larry C., Goldin, Alan L., Lester, Henry A., Lübbert, Hermann, Marshall, John, Snutch, Terry P.   +11 more
core  

Ring-Expansion Metathesis Polymerization: Catalyst-Dependent Polymerization Profiles [PDF]

, 2009
Ring-expansion metathesis polymerization (REMP) mediated by recently developed cyclic Ru catalysts has been studied in detail with a focus on the polymer products obtained under varied reaction conditions and catalyst architectures.
Boydston, Andrew J., Gorodetskaya, Irina A., Grubbs, Robert H., Kornfield, Julia A., Spiess, Hans W., Xia, Yan, Yao, Yefeng   +6 more
core   +2 more sources

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source