Results 71 to 80 of about 765,777 (264)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Correlação entre o Índice de Fluxo à Fusão e a Função da Distribuição de Cisão de Cadeia durante a degradação termo-mecânica do polipropileno Correlation between Melt Flow Index and Chain Scission Distribution Function during the thermo-mechanical degradation of polypropylene

open access: yesPolímeros, 2006
Mudanças no Índice de Fluxo à Fusão (MFI) foram correlacionadas com o deslocamento da curva de distribuição de massa molar (MWD) geradas pela degradação termo-mecânica do polipropileno (PP) sujeito a múltiplas extrusões.
Carlos A. Cáceres C.   +1 more
doaj   +1 more source

Molecular Weight Distribution of Polypropylene

open access: yesKobunshi Kagaku, 1965
Ziegler-Natta触媒で合成したポリプロピレンの分子量分布を沈殿濁度法*1により測定し, 累積重量分率I (M) =5-95%の範囲で対数正規分布に近似されることを確かめた。しかし実測のデータは上記範囲外, 特に高分子量領域で対数正規分布からずれてくるものが多く, 直線の勾配から計算される重量平均分子量Mwおよび数平均分子量Mnはかなりの誤差を伴う。著者らは高分子端の補正を行なった修正対数正規分布を適用することにより, これを解決することができた。また, 対数正規分布の場合には, Mnと併用してQ値 (=Mw/Mn) を相対的な不均一性を表わす尺度として採用しうることを考察した。
Sanae Tanaka   +2 more
openaire   +3 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Effects of Pretreatment Methods on Extraction, Separation, and Processing Properties of Chlorella Protein

open access: yesShipin gongye ke-ji
To explore the effects of various pretreatment methods on the extraction, separation, and processing properties of Chlorella protein, freezing, freeze-drying, and spray-drying were applied.
Shuaiyi GUO   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Comparison of intrinsic characteristics and properties of natural rubber from different origins

open access: yesHecheng xiangjiao gongye
Molecular weight and its distribution, gel content, nitrogen and phosphorus content, wet strength, Mooney viscosity, mechanical properties and aging resistance of three kinds of domestic raw natural rubber were compared with those of imported ribbed ...
ZHAO Xin, ZHANG Hao, SUN Quan, JING Yu-long, JIANG Mei-juan, YANG Jing-ting, DU Ming-xin
doaj   +1 more source

Production of resistant maltodextrin and starch as novel prebiotics by the reaction of maltodextrin and starch with malic acid and citric acid [PDF]

open access: yesActa Universitatis Sapientiae: Alimentaria
Resistant maltodextrin and starch are indigestible food components that reach the colon intact, serving as nutrients for Bifidobacteria and Lactobacilli. As typical dietary fibre, they are among the most beneficial due to higher solubility in water. In
Cs. Albert, J. Csapó, B. Kovács
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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