Results 91 to 100 of about 774,640 (308)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The molecular weight and molecular weight distribution of hydroxypropyl methylcellulose used in the film coating of tablets

open access: yes, 1980
The molecular weight and molecular weight distributions of nine grades of hydroxypropyl methylcellulose used in the film coating of tablets have been measured using gel permeation chromatography.
R C Rowe
core   +1 more source

Determinations of Molecular Weight and Molecular Weight Distribution of High Polymers by the Rheological Properties

open access: yes, 1989
Several methods are reviewed by which the molecular weight (MW) and molecular weight distribution (MWD) of polymeric material were determined from the rheological properties. A poly (arylene ether) polymer with six different molecular weights was used in
Huang, Joan Y. Z.
core   +4 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The Molecular Weight Characterisation of Pinus radiata Bark Condensed Tannins

open access: yes, 2007
Crude condensed tannins extracted from Pinus radiata bark (sourced from Tokoroa) with various solvents (Hot water (HW), methanol/water/acetic acid (MWA), acetone/water (AW) and hot aqueous 2% sulphite/urea solution (SFU)) were subjected to Sephadex LH-20
Bogun, Ben Rowan
core  

Molecular-Weight Distribution of Living Chains in Polystyrene Prepared by Reversible Addition–Fragmentation Chain-Transfer Polymerization

open access: yes, 2019
We report on the chromatographic separation and characterization of living chains in polystyrene prepared by reversible addition–fragmentation chain-transfer (RAFT) polymerization.
Mirim Park (7433702)   +7 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Fitting molecular weight distributions using a log-normal distribution model

open access: yes, 2015
‘Living’ radical polymerization has opened the way to producing complex polymer architectures, including cyclic polymers, dendrimers, stars and many other structures.
Monteiro, Michael J.
core   +1 more source

Production of resistant maltodextrin and starch as novel prebiotics by the reaction of maltodextrin and starch with malic acid and citric acid [PDF]

open access: yesActa Universitatis Sapientiae: Alimentaria
Resistant maltodextrin and starch are indigestible food components that reach the colon intact, serving as nutrients for Bifidobacteria and Lactobacilli. As typical dietary fibre, they are among the most beneficial due to higher solubility in water. In
Cs. Albert, J. Csapó, B. Kovács
doaj   +1 more source

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