Results 101 to 110 of about 765,777 (264)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

High-cytocompatible semi-IPN bio-ink with wide molecular weight distribution for extrusion 3D bioprinting. [PDF]

Sci Rep, 2022
Li M, Shi T, Yao D, Yue X, Wang H, Liu K.   +5 more
europepmc   +1 more source

Obtention and Characterisation of Antioxidant-Rich Peptides from Defatted Grape Seed Meal Using Different Enzymes

Foods
Defatted grape seed meal (DGSM) is a residue obtained from grape pomace and is an important source of protein. The aim of this study was to select peptides with optimal antioxidant and colour properties, obtained using enzymes of different origins and ...
María del Rosario Rodríguez-Muñoz, Ana Belén Mora-Garrido, Francisco J. Heredia, María Jesús Cejudo-Bastante, María Lourdes González-Miret   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Precise Control of Both Dispersity and Molecular Weight Distribution Shape by Polymer Blending. [PDF]

Angew Chem Int Ed Engl, 2021
Whitfield R, Truong NP, Anastasaki A.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Thermal Pyrolysis of Polystyrene Aided by a Nitroxide End-Functionality Improved Process and Modeling of the Full Molecular Weight Distribution. [PDF]

Polymers (Basel), 2021
Monroy-Alonso A, Ordaz-Quintero A, Ramirez JC, Saldívar-Guerra E.   +3 more
europepmc   +1 more source

Effect of Different Proteases on the Enzymatic Hydrolysis Efficiency and Structure of Wheat Gluten

Shipin gongye ke-ji
This study aimed to investigate the enzymatic hydrolysis effects of papain, alkaline protease, neutral protease, alkaline protease TG enzyme combination, and papain alkaline protease combination on gluten protein and their impact on its structure.
Xiangjun LIU, Yuting ZHANG, Xuedong WANG, Yan WU, Ku LI, Huai XU   +5 more
doaj   +1 more source

Rheological Method for Determining Molecular Weight and Molecular Weight Distribution

, 2012
Gel permeation chromatography (GPC) method is a widely used and accepted method for measuring the MW and MWD for polymers. However, the method has its limitations. The key of this method is to find the suitable solvents to dissolve the polymer well. But cellulose can not be dissolved in most of the organic solvents because of the interand introhydrogen
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source