Results 111 to 120 of about 3,841,010 (347)

Drug selection for inner ear therapy

Frontiers in Pharmacology
IntroductionOne of the primary tenets in pharmacotherapy is that the applied drug must reach the target tissue at therapeutic concentration. For many therapies intended to treat hearing disorders it has become apparent that we have failed to achieve this
Alec N. Salt, Jeremy G. Turner
doaj   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Interrelations of Quantum-Mechanical Quantities Concerning Chemical Reactivity of Conjugated Molecules [PDF]

, 1957
Kenichi Fukui, Teijiro Yonezawa, Chikayoshi Nagata   +2 more
openalex   +1 more source

Molecular Model Spatial Ability Test Development Study

Journal of the Turkish Chemical Society Section C Chemical Education, 2018
There is positive correlation between chemistry achievement and spatial ability. Because, chemistry includes spatial concepts such as; molecule, molecular geometry and isomerism.
Soner Yavuz, Cem Büyükekşi
doaj  

The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts

Nature Communications, 2016
In response to intracellular signals, bacterial translational riboswitches embedded in mRNAs can regulate gene expression through inhibition of translation initiation.
Arlie J. Rinaldi, Paul E. Lund, Mario R. Blanco, Nils G. Walter   +3 more
doaj   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

Errata: Quantum-Mechanical Resonance between Identical Molecules [PDF]

, 1950
Herbert Jehle
openalex   +1 more source

COMPUTER SIMULATION OF STRUCTURAL FRAGMENTS OF COAL ORGANIC MASS

Вестник Кемеровского государственного университета, 2014
Hybrid B3LYP and gradient SLYP functionals were used to reveal the structure of organic mass of coal within the density functional theory in the basis of local orbitals. For all modeled compounds a number of important characteristics was identified – the
A. N. Porohnov, Yu. N. Zhuravlev
doaj  

The cytochrome oxidase defect in ISC‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm22

FEBS Letters, EarlyView.
The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff, Dominik Trauth, Weronika Śliwińska, Linda Boss, Roland Lill   +4 more
wiley   +1 more source

THE ORIENTATION OF MOLECULES IN SURFACES, SURFACE ENERGY, ADSORPTION, AND SURFACE CATALYSIS. V. THE ADHESIONAL WORK BETWEEN ORGANIC LIQUIDS AND WATER.¹ [PDF]

, 1920
William D. Harkins, George L. Clark, Lathrop E. Roberts   +2 more
openalex   +1 more source