Results 111 to 120 of about 5,474,193 (390)

Effect of ECAP and volume ultrasonic treatment on the corrosion resistance of magnesium [PDF]

BIO Web of Conferences
Magnesium and its alloys are promising materials for manufacturing bioresorbable implants. Various combinations of thermo-mechanical processing are used to improve the mechanical properties and corrosion resistance of magnesium alloys, forming the ...
Aksenov Denis, Nazarov Airat, Shishkunova Maria, Asfandiyarov Rashid, Sementeeva Yulia   +4 more
doaj   +1 more source

SwissDock, a protein-small molecule docking web service based on EADock DSS

Nucleic Acids Res., 2011
Most life science processes involve, at the atomic scale, recognition between two molecules. The prediction of such interactions at the molecular level, by so-called docking software, is a non-trivial task.
A. Grosdidier, V. Zoete, O. Michielin
semanticscholar   +1 more source

THE ARCHITECTURE OF MOLECULES [PDF]

Proceedings of the National Academy of Sciences, 1964
Molecular architecture may be said to have originated in 1874, when J. H. van't Hoff and J. A. le Bel independently formulated the brilliant postulate that the four valence bonds of the carbon atom are directed approximately toward the corners of a regular tetrahedron. It was extended into inorganic chemistry in 1893, when A.
openaire   +3 more sources

Carbon nanotube sensor for vibrating molecules

, 2013
The transport properties of a CNT capacitively coupled to a molecule vibrating along one of its librational modes are studied and its transport properties analyzed in the presence of an STM tip.
Cavaliere, F., Dolcetto, G., Remaggi, F., Sassetti, M., Ziani, N. Traverso   +4 more
core   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Pathways and molecules for overcoming immunotolerance in metastatic gastrointestinal tumors

Frontiers in Immunology
Worldwide, gastrointestinal (GI) cancer is recognized as one of the leading malignancies diagnosed in both genders, with mortality largely attributed to metastatic dissemination.
Qixin Gan, Yue Li, Yuejun Li, Haifen Liu, Daochuan Chen, Lanxiang Liu, Churan Peng   +6 more
doaj   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Effect of Molecules’ Physicochemical Properties on Whey Protein/Alginate Hydrogel Rheology, Microstructure and Release Profile

Pharmaceutics
The encapsulation of molecules with different physicochemical properties (theophylline, blue dextran, salicylic acid and insulin) in whey protein (WP) and alginate (ALG) microparticles (MP) for oral administration was studied.
A. Delanne-Cuménal, E. Lainé, V. Hoffart, V. Verney, G. Garrait, E. Beyssac   +5 more
doaj   +1 more source

Biological Effect of Associated Water Molecules [PDF]

, 1932
H. T. Barnes, T. Cunliffe Barnes
openalex   +1 more source