Results 121 to 130 of about 5,095,036 (399)
The Area Law of Molecular Entropy: Moving beyond Harmonic Approximation
This article shows that the gas-phase entropy of molecules is proportional to the area of the molecules, with corrections for the different curvatures of the molecular surface.
Amitava Roy+2 more
doaj +1 more source
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri+8 more
wiley +1 more source
Effect of ECAP and volume ultrasonic treatment on the corrosion resistance of magnesium [PDF]
Magnesium and its alloys are promising materials for manufacturing bioresorbable implants. Various combinations of thermo-mechanical processing are used to improve the mechanical properties and corrosion resistance of magnesium alloys, forming the ...
Aksenov Denis+4 more
doaj +1 more source
DNA unwinding heterogeneity by RecBCD results from static molecules able to equilibrate. [PDF]
Single-molecule studies can overcome the complications of asynchrony and ensemble-averaging in bulk-phase measurements, provide mechanistic insights into molecular activities, and reveal interesting variations between individual molecules.
Baskin, Ronald J+2 more
core
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten+10 more
wiley +1 more source
Melatonin: an ancient molecule that makes oxygen metabolically tolerable
Melatonin is remarkably functionally diverse with actions as a free radical scavenger and antioxidant, circadian rhythm regulator, anti‐inflammatory and immunoregulating molecule, and as an oncostatic agent.
L. Manchester+8 more
semanticscholar +1 more source
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung+6 more
wiley +1 more source
Vortex molecules in coherently coupled two-component Bose-Einstein condensates
A vortex molecule is predicted in rotating two-component Bose-Einstein condensates whose internal hyperfine states are coupled coherently by an external field. A vortex in one component and that in the other are connected by a domain wall of the relative
D. Yoshioka+6 more
core +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher+6 more
wiley +1 more source
Exciton Binding Energy in small organic conjugated molecule [PDF]
For small organic conjugated molecules the exciton binding energy can be calculated treating molecules as conductor, and is given by a simple relation BE \approx e2/(4{\pi}{\epsilon}0{\epsilon}R), where {\epsilon} is the dielectric constant and R is the equivalent radius of the molecule.
arxiv