Results 121 to 130 of about 3,473,423 (297)
Restriction of intramolecular movements within the Cry1Aa toxin molecule of Bacillus thuringiensis through disulfide bond engineering [PDF]
, 1997 Jean‐Louis Schwartz +6 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The effects of macromolecular crowding on the mechanical stability of protein molecules [PDF]
, 2008 Jian‐Min Yuan +6 more
openalex +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Molecular Model Spatial Ability Test Development Study
Journal of the Turkish Chemical Society Section C Chemical Education, 2018 There is positive correlation between chemistry achievement and spatial ability. Because, chemistry includes spatial concepts such as; molecule, molecular geometry and isomerism.
Soner Yavuz, Cem Büyükekşi
doaj
Enhancing High-Order Harmonic Generation in Light Molecules by Using Chirped Pulses [PDF]
, 2016 Manuel Lara‐Astiaso +5 more
openalex +1 more source
Molecular Oncology, Volume 19, Issue 12, Page 3613-3633, December 2025.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
COMPUTER SIMULATION OF STRUCTURAL FRAGMENTS OF COAL ORGANIC MASS
Вестник Кемеровского государственного университета, 2014 Hybrid B3LYP and gradient SLYP functionals were used to reveal the structure of organic mass of coal within the density functional theory in the basis of local orbitals. For all modeled compounds a number of important characteristics was identified – the
A. N. Porohnov, Yu. N. Zhuravlev
doaj
Molecular Oncology, Volume 19, Issue 12, Page 3548-3577, December 2025.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source