Results 171 to 180 of about 5,323,640 (377)

The biosynthesis of kojic acid. 3. The incorporation of labelled small molecules into kojic acid [PDF]

, 1953
H. R. V. Arnstein, Ronald Bentley
openalex   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

The Electronic Structure of the Normal Nitrous Oxide Molecule [PDF]

, 1932
Linus Pauling
openalex   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

ON THE REACTIONS OF BOTH THE IONS AND THE MOLECULES OF ACIDS, BASES AND SALTS. THE REACTIONS OF SODIUM ETHYLATE WITH METHYL IODIDE IN ABSOLUTE ETHYL ALCOHOL AT 25°.⁴ [TWENTY-FIRST⁵ COMMUNICATION ON CATALYSIS.] [PDF]

, 1915
Hayden Robertson, S. F. Acree
openalex   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

In silico formulation optimization and particle engineering of pharmaceutical products using a generative artificial intelligence structure synthesis method

Nature Communications
Pharmaceutical drug dosage forms are critical for ensuring the effective and safe delivery of active pharmaceutical ingredients to patients. However, traditional formulation development often relies on extensive lab and animal experimentation, which can ...
Timothy Hornick, Chen Mao, Athanas Koynov, Phillip Yawman, Prajwal Thool, Karthik Salish, Morgan Giles, Karthik Nagapudi, Shawn Zhang   +8 more
doaj   +1 more source

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Nature Network Boston, 2015
Rebecca C. Coll, A. Robertson, J. Chae, Sarah C. Higgins, Raúl Muñoz-Planillo, Marco C. Inserra, I. Vetter, Lara S. Dungan, Brian G. Monks, A. Stutz, Daniel E. Croker, M. Butler, M. Haneklaus, Caroline E. Sutton, G. Núñez, E. Latz, D. Kastner, K. Mills, S. Masters, K. Schroder, M. Cooper, L. O’Neill   +21 more
semanticscholar   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

CCXLVII.—The chemistry of the glutaconic acids. Part I. Methods for the preparation of the alkylglutaconic acids which prove the identity of the α- and γ-positions in the glutaconic acid molecule [PDF]

, 1911
Ferdinand Bernard Thole, Jocelyn Field Thorpe   +1 more
openalex   +1 more source