Results 71 to 80 of about 5,474,193 (390)

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

From molecules in space to molecules in breath [PDF]

Paediatric Respiratory Reviews, 2016
The evolution of the selected ion flow tube, SIFT, used to study ion-molecule reactions of interstellar significance, to the selected ion flow tube mass spectrometry, SIFT-MS, analytical technique is described briefly. Focus is placed on the application of SIFT-MS to breath analysis and its potential for the detection of volatile biomarkers of disease ...
openaire   +3 more sources

Current Profiles of Molecular Nanowires; DFT Green Function Representation

, 2004
The Liouville-space Green function formalism is used to compute the current density profile across a single molecule attached to electrodes. Time ordering is maintained in real, physical, time, avoiding the use of artificial time loops and backward ...
A. Bachtold, A. Nitzan, A. Nitzan, A.A. Stuchebrukhov, C. Joachim, C.P. Collier, D.S. Kosov, D.S. Kosov, H.B. Weber, I. Lee, J. Reichert, J. Schwinger, J.R. Heath, L.V. Keldysh, M. Di Ventra, M.A. Reed, M.S. Gudiksen, N.D. Lang, N.D. Lang, N.D. Lang, O. Berman, O. Berman, Oleg Berman, S. Mukamel, S. Tretiak, Shaul Mukamel, V. Chernyak, V. Mujica, V. Mujica, X.D. Cui, Y. Xue, Y. Xue   +31 more
core   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

FEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic, Morana Dulic, Ita Gruic‐Sovulj   +2 more
wiley   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Concepts in the design and engineering of single-molecule electronic devices

Nature Reviews Physics, 2019
Over the past two decades, various techniques for fabricating nano-gapped electrodes have emerged, promoting rapid development in the field of single-molecule electronics, on both the experimental and theoretical sides.
Na Xin, Jianxin Guan, Chenguang Zhou, Xinjiani Chen, Chunhui Gu, Yu Li, M. Ratner, A. Nitzan, J. Stoddart, Xuefeng Guo   +9 more
semanticscholar   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4

Journal of Experimental Medicine, 1999
Toll-like receptor 4 (TLR4) is a mammalian homologue of Drosophila Toll, a leucine-rich repeat molecule that can trigger innate responses against pathogens.
Rintaro Shimazu, S. Akashi, H. Ogata, Y. Nagai, K. Fukudome, K. Miyake, M. Kimoto   +6 more
semanticscholar   +1 more source

Single-molecule pulling: phenomenology and interpretation

, 2013
Single-molecule pulling techniques have emerged as versatile tools for probing the noncovalent forces holding together the secondary and tertiary structure of macromolecules. They also constitute a way to study at the single-molecule level processes that
Allinger, Ashkin, Basu, Berendsen, Bustamante, Camden, Chodera, Crooks, Evans, Ferrenberg, Franco, Franco, Franco, Frenkel, Freund, Gebhardt, Gunari, Halperin, Harris, Harvey, Hess, Heymann, Hoover, Hub, Huguet, Hummer, Hummer, Hummer, Imparato, Isralewitz, Izrailev, Jarzynski, Jarzynski, Jarzynski, Jarzynski, Kim, Kirkwood, Kirmizialtin, Kreuzer, Kubo, Kumar, Lee, Liphardt, Liphardt, Marsili, Martyna, McCullagh, Minh, Moerner, Neuman, Newman, Nitzan, Nosé, Oberhauser, Park, Phillips, Pohorille, Rief, Ritort, Roux, Rubinstein, Schäfer, Strick, Süzen, Thijssen, Weiss   +65 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source