Results 71 to 80 of about 3,175,530 (158)

Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88

open access: yesBMC Biology, 2018
Background Higher-order self-assembly of proteins, or “prion-like” polymerisation, is now emerging as a simple and robust mechanism for signal amplification, in particular within the innate immune system, where the recognition of pathogens or danger ...
Ailís O’Carroll   +11 more
doaj   +1 more source

DNA unwinding heterogeneity by RecBCD results from static molecules able to equilibrate. [PDF]

open access: yes, 2013
Single-molecule studies can overcome the complications of asynchrony and ensemble-averaging in bulk-phase measurements, provide mechanistic insights into molecular activities, and reveal interesting variations between individual molecules.
Baskin, Ronald J   +2 more
core  

Non-Linear Transport through a Molecular Nanojunction

open access: yes, 2001
We present a simple model of electrical transport through a metal-molecule-metal nanojunction that includes charging effects as well as aspects of the electronic structure of the molecule.
Hettler, Matthias H.   +2 more
core   +2 more sources

As4Se4 crystal versus As4Se4 molecule: A plane wave DFT study of the geometric and electronic structure

open access: yesPhysics of Complex Systems
Сhalcogenide crystals reveal a wide range of changes in chemical and physical properties under band gap light illumination. A majority of these properties are determined by the electronic structure.
Антон Андреевич Гавриков   +2 more
doaj   +1 more source

Spin-dependent heat signatures of single-molecule spin dynamics

open access: yes, 2019
We investigate transient spin-dependent thermoelectric signatures in a single-molecule magnet under the effect of a time-dependent voltage pulse. We model the system using nonequilibrium Green's functions and a generalized spin equation of motion ...
Fransson, Jonas   +2 more
core   +1 more source

Effect of Molecules’ Physicochemical Properties on Whey Protein/Alginate Hydrogel Rheology, Microstructure and Release Profile

open access: yesPharmaceutics
The encapsulation of molecules with different physicochemical properties (theophylline, blue dextran, salicylic acid and insulin) in whey protein (WP) and alginate (ALG) microparticles (MP) for oral administration was studied.
A. Delanne-Cuménal   +5 more
doaj   +1 more source

DeSci EDU: course design and self-perceived evaluation in decentralized science education

open access: yesFrontiers in Blockchain
IntroductionDecentralized science (DeSci) aims to address structural inefficiencies in traditional research yet lacks formal educational pathways.MethodsThis exploratory case study develops and evaluates an eight-week blended course, DeSci EDU, which ...
S. Espinoza   +8 more
doaj   +1 more source

Targeted dual selection to optimize transposon stable pool generation of multispecifics

open access: yesmAbs
Growing knowledge around disease states has led to opportunities within research to make designer molecules with improved specificity and broader efficacy.
Julie Johnston   +9 more
doaj   +1 more source

Non-Markovian full counting statistics in quantum dot molecules

open access: yes, 2015
Full counting statistics of electron transport is a powerful diagnostic tool for probing the nature of quantum transport beyond what is obtainable from the average current or conductance measurement alone.
Jiao, Hu-Jun   +3 more
core   +1 more source

Codon deoptimization of multispecific biologics reduces mispairing during transient mammalian protein expression

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionCodon optimization is utilized in biologics design to maximize protein expression. Selecting the host organism’s most frequently used codons for each amino acid can significantly enhance recombinant protein expression yields.
Timothy Z. Chang   +10 more
doaj   +1 more source

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