Results 71 to 80 of about 2,242,520 (263)
Discovery of a Small-Molecule-Dependent Photolytic Peptide
, 2020 We accidentally found that YM-53601, a known small-molecule inhibitor of squalene synthase (SQS), selectively depletes SQS from mammalian cells upon UV irradiation.
Louvy Lynn Punzalan (8269551) +5 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Pathways and molecules for overcoming immunotolerance in metastatic gastrointestinal tumors
Frontiers in ImmunologyWorldwide, gastrointestinal (GI) cancer is recognized as one of the leading malignancies diagnosed in both genders, with mortality largely attributed to metastatic dissemination.
Qixin Gan +6 more
doaj +1 more source
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2013 This article describes cluster model of gaseous materials and prospects of using the model. Equations set for the calculation of different sizes clusters concentrations are presented. The authors produce numerical solution of the equation set. Results of
Alexey Bublikov +2 more
doaj +1 more source
Electron-molecule collisions at low and intermediate energies using the R-matrix method [PDF]
, 2005 We present the latest developments of the R-matrix method as applied to electron-molecule collisions. A variety of calculations for H2O are presented including the study of rotational excitation and preliminary data for dissociative electron attachment ...
Tennyson, J. +15 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2013 Certain heritage collections get cyclically infested by pest insects. Currently used curative treatments are punctual eradication operations, but in no way do they prevent the chronic re-infestations of sensitive cultural objects.
Grazia Nicosia +3 more
doaj +1 more source
Molecule-Based Materials: The Structural Network Approach
, 2005 The properties of a material depend not only on the specific atoms and molecules it contains, but also on the arrangement of these in space. Many of these three-dimensional arrangements are described as "3D-nets" or "3D-networks".
Larsson, K. +5 more
core +1 more source
The complexity of mesoporous silica nanomaterials unravelled by single molecule microscopy [PDF]
, 2011 Mesoporous silica nanomaterials are a novel class of materials that offer a highly complex porous network with nanometre-sized channels into which a wide amount of differently sized guests can be incorporated.
Bräuchle, Christoph +5 more
core +1 more source