Results 71 to 80 of about 2,067,232 (315)

Object approach to the organic molecule representation

, 2022
Object way of thinking about structure of organic molecule (functional groups, cycles) is common for professional synthetic chemists. In contrast, atom-level graph-based approaches mostly used for computing.
Yehor, Malets
core   +1 more source

Molecules and Psychiatry [PDF]

American Journal of Psychiatry, 2015
While the importance of molecules for psychiatry today may not be immediately obvious, the articles on molecular mechanisms in this issue represent groundbreaking research (1–5). They concern themselves with specific molecular mechanisms of psychopathology in schizophrenia, bipolar disorder, and depression.
openaire   +2 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Aptamer Recognition of Multiplexed Small-Molecule-Functionalized Substrates [PDF]

, 2018
Aptamers are chemically synthesized oligonucleotides or peptides with molecular recognition capabilities. We investigated recognition of substrate-tethered small-molecule targets, using neurotransmitters as examples, and fluorescently labeled DNA ...
Andrea M. Kasko (801217), Andrea M. Kasko, Kasko, Andrea M, Melkonian, Arin L, Paul S. Weiss (1272021), Huan H. Cao (1477843), Anne M. Andrews, Nako Nakatsuka (1477846), Arin L. Melkonian (5484239), Paul S. Weiss, Nako Nakatsuka, Huan H. Cao, Stephanie Deshayes, Arin L. Melkonian, Anne M. Andrews (1454776), Cao, Huan H, Stephanie Deshayes (1336377), Weiss, Paul S, Nakatsuka, Nako, Andrews, Anne M, Deshayes, Stephanie   +20 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Update on the Development of Toehold Switch-Based Approach for Molecular Diagnostic Tests of COVID-19

Journal of Nucleic Acids, 2022
A high volume of diagnostic tests is needed during the coronavirus disease 2019 (COVID-19) pandemic to obtain representative results. These results can help to design and implement effective policies to prevent the spread of severe acute respiratory ...
Almando Geraldi, Ni Nyoman Tri Puspaningsih, Fatiha Khairunnisa   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Artificial Nonlinearity Generated from Electromagnetic Coupling Meta-molecule

, 2018
A purely artificial mechanism for optical nonlinearity is proposed based on a metamaterial route. The mechanism is derived from classical electromagnetic interaction in a meta-molecule consisting of a cut-wire meta-atom nested within a split-ring meta ...
Yongzheng Wen (5937644), Ji Zhou (481629)   +1 more
core   +1 more source

A Memristive Element Based on an Electrically Controlled Single‐Molecule Reaction [PDF]

, 2020
A single-molecule memory element is electrically-controlled using two distinct reaction mechanisms as reported by K. Moth-Poulsen, J. Hihath, and co-workers (DOI:10.1002/anie.202002300).
Haipeng B. Li, Joshua Hihath, Behabitu E. Tebikachew, Li, Haipeng B., Tebikachew, Behabitu Ergette, Kasper Moth‐Poulsen, Tebikachew, Behabitu Ergette,, Hihath, Joshua,, Hihath, Joshua, Wiberg, Cedrik, Cedrik Wiberg, Moth-Poulsen, Kasper,, Li, Haipeng B.,, Wiberg, Cedrik,, Moth-Poulsen, Kasper   +14 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source