Results 81 to 90 of about 5,095,036 (399)
MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4
Journal of Experimental Medicine, 1999 Toll-like receptor 4 (TLR4) is a mammalian homologue of Drosophila Toll, a leucine-rich repeat molecule that can trigger innate responses against pathogens.
Rintaro Shimazu +6 more
semanticscholar +1 more source
, 2010 Theoretical approaches of electronic transport in correlated molecules usually consider an extended molecule, which includes, in addition to the molecule itself, parts of electrodes.
Abrikosov A. A. +9 more
core +1 more source
Massively parallel single-molecule manipulation using centrifugal force [PDF]
, 2009 Precise manipulation of single molecules has already led to remarkable insights in physics, chemistry, biology and medicine. However, widespread adoption of single-molecule techniques has been impeded by equipment cost and the laborious nature of making ...
Bell +18 more
core +3 more sources
Ligand recognition by 14‐3‐3 proteins requires negative charges but not necessarily phosphorylation
FEBS Letters, EarlyView.Interactions of 14‐3‐3 proteins with their binding partners are attributed to phosphorylation of the binding partners. In this work, we show that at least one negative charge is required for the peptides to bind 14‐3‐3ε, although phosphorylation is not necessary, and that two negative charges are preferable for high affinity binding.
Seraphine Kamayirese +2 more
wiley +1 more source
3CLpro inhibitors: DEL-based molecular generation
Frontiers in Pharmacology, 2022 Molecular generation (MG) via machine learning (ML) has speeded drug structural optimization, especially for targets with a large amount of reported bioactivity data.
Feng Xiong +18 more
doaj +1 more source
, 2011 We study the possibility to use interaction between a polar molecule in the ground electronic and vibrational state and a Rydberg atom to construct two-qubit gates between molecular qubits and to coherently control molecular states.
Amano +30 more
core +1 more source
Reaction kinetics of ultracold molecule-molecule collisions [PDF]
Nature Communications, 2018 AbstractStudying chemical reactions on a state-to-state level tests and improves our fundamental understanding of chemical processes. For such investigations it is convenient to make use of ultracold atomic and molecular reactants as they can be prepared in well defined internal and external quantum states.
Daniel K. Hoffmann +4 more
openaire +8 more sources
Calcium‐sensing receptor‐ and ADAM10‐mediated klotho shedding is regulated by tetraspanin 5
FEBS Letters, EarlyView.The G protein‐coupled calcium‐sensing receptor (CaSR) and the disintegrin/metalloprotease ADAM10 in the renal distal convoluted tubule control systemic levels of Klotho, a cell and tissue homeostasis‐preserving factor. We show that CaSR‐induced cleavage of membrane‐bound αKlotho by ADAM10 requires tetraspanin 5 (Tspan5), a scaffolding and chaperone ...
Zhenan Liu +4 more
wiley +1 more source
Chaotic internal dynamics of dissipative optical soliton molecules [PDF]
arXiv, 2022 When a laser cavity supports the propagation of several ultrashort pulses, these pulses interact and can form compact bound states called soliton molecules. Soliton molecules are fascinating objects of nonlinear science, which present striking analogies with their matter molecules counterparts.
arxiv