Results 81 to 90 of about 3,518,193 (347)

Pathways and molecules for overcoming immunotolerance in metastatic gastrointestinal tumors

Frontiers in Immunology
Worldwide, gastrointestinal (GI) cancer is recognized as one of the leading malignancies diagnosed in both genders, with mortality largely attributed to metastatic dissemination.
Qixin Gan, Yue Li, Yuejun Li, Haifen Liu, Daochuan Chen, Lanxiang Liu, Churan Peng   +6 more
doaj   +1 more source

USING OF NUMERICAL METHODS FOR CALCULATION THE EQUATION FOR CLUSTERS CONCENTRATIONS IN GASEOUS MATERIALS

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2013
This article describes cluster model of gaseous materials and prospects of using the model. Equations set for the calculation of different sizes clusters concentrations are presented. The authors produce numerical solution of the equation set. Results of
Alexey Bublikov, Natalia Denisova, Tamara Segeda   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Ultracold Rydberg molecules [PDF]

Nature Communications, 2018
AbstractUltracold molecules formed from association of a single Rydberg atom with surrounding atoms or molecules and those from double Rydberg excitations are discussed in this review. Ultralong-range Rydberg molecules possess a novel molecular bond resulting from scattering of the Rydberg electron from the perturber atoms or molecules.
J. P. Shaffer, S. T. Rittenhouse, H. R. Sadeghpour   +2 more
openaire   +4 more sources

Effect of Molecules’ Physicochemical Properties on Whey Protein/Alginate Hydrogel Rheology, Microstructure and Release Profile

Pharmaceutics
The encapsulation of molecules with different physicochemical properties (theophylline, blue dextran, salicylic acid and insulin) in whey protein (WP) and alginate (ALG) microparticles (MP) for oral administration was studied.
A. Delanne-Cuménal, E. Lainé, V. Hoffart, V. Verney, G. Garrait, E. Beyssac   +5 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Electron Accumulative Molecules [PDF]

Journal of the American Chemical Society, 2018
With the goal to produce molecules with high electron accepting capacity and low reorganization energy upon gaining one or more electrons, a synthesis procedure leading to the formation of a B-N(aromatic) bond in a cluster has been developed. The research was focused on the development of a molecular structure able to accept and release a specific ...
Buades, Ana B., Arderiu, Victor Sanchez, Olid-Britos, David, Viñas, Clara, Sillanpää, Reijo, Haukka, Matti, Fontrodona, Xavier, Paradinas, Marcos, Ocal, Carmen, Teixidor, Francesc   +10 more
openaire   +3 more sources

Isoprene: An Antioxidant to Guard Plants against Stress

International Journal of Plant Biology
Isoprene, a lipophilic and unstable compound with the chemical formula C5H8, is transported to plant chloroplasts via the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway, which relies on photosynthesis. Although only about 20% of terrestrial plants can
Perumalla Srikanth, Ann Maxton, Sam A. Masih, Adriano Sofo, Nafees A. Khan   +4 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

As4Se4 crystal versus As4Se4 molecule: A plane wave DFT study of the geometric and electronic structure

Physics of Complex Systems
Сhalcogenide crystals reveal a wide range of changes in chemical and physical properties under band gap light illumination. A majority of these properties are determined by the electronic structure.
Антон Андреевич Гавриков, Владимир Георгиевич Кузнецов, Владимир Андреевич Трепаков   +2 more
doaj   +1 more source