Results 101 to 110 of about 103,985 (285)

High harmonic generation from axial chiral molecules

Optics Express, 2017
Axial chiral molecules, whose stereogenic element is an axis rather than a chiral center, have attracted widespread interest due to their important application, such as asymmetric synthesis and chirality transfer. We investigate high harmonic generation from axial chiral molecules with bichromatic counterrotating circularly polarized laser fields. High
Dian, Wang, Xiaosong, Zhu, Xi, Liu, Liang, Li, Xiaofan, Zhang, Pengfei, Lan, Peixiang, Lu   +6 more
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Multimodality Imaging Probe for Positron Emission Tomography and Fluorescence Imaging Studies

Molecular Imaging, 2014
Our goal is to develop multimodality imaging agents for use in cell tracking studies by positron emission tomography (PET) and optical imaging (OI).
Suresh K. Pandey, Jasmeet Kaur, Balu Easwaramoorthy, Ankur Shah, Robert Coleman, Jogeshwar Mukherjee   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

An approach to calculate Franck-Condon factors involving anharmonic potentials using harmonic oscillator bases

Journal of Physics Communications
In this contribution a discrete variable representation (DVR) approach to calculate Franck-Condon factors (FCFs) is presented. The method is illustrated using a harmonic oscillator basis. The advantage of this approach is that it is possible to calculate
E Suárez, R Lemus
doaj   +1 more source

Proteome-metabolome profiling of wax gland complex reveals functional changes in honeybee, Apis mellifera L.

iScience
Summary: Wax gland complex (WGC) serves as the primary generator of beeswax; however, the dynamic biological function in wax secretion remains unclear. To elucidate the developmental mechanism of WGC, we conducted a comprehensive analysis to reveal the ...
Rumeng Xu, Beibei Ma, Yiying Yang, Xuancheng Dong, Jianke Li, Xiang Xu, Yu Fang   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Orthogonal Experiments on Ozone Oxidation Denitration of Sintering Flue Gas

E3S Web of Conferences, 2018
Ozone oxidation denitration process has become the most closely watched sintering flue gas denitration technology currently. In order to investigate the influence of different operating conditions on NO oxidation in practical engineering application of ...
Yang Yingxin, Zhong Lu, Xue Xueliang, Hu Jingling, Hu Xiaotu, Liu Yong   +5 more
doaj   +1 more source

Controlled Molecule Generator for Optimizing Multiple Chemical Properties. [PDF]

ACM CHIL 2021 (2021), 2021
Shin B, Park S, Bak J, Ho JC.
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source