Results 91 to 100 of about 877,283 (253)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

NIR-activatable nitric oxide generator based on nanoparticles loaded small-molecule photosensitizers for synergetic photodynamic/gas therapy

Journal of Nanobiotechnology
Background Therapeutic approaches that combine conventional photodynamic therapy (PDT) with gas therapy (GT) to sensitize PDT are an attractive strategy, but the molecular structure design of the complex lacks effective guiding strategies. Results Herein,
Lili Fu, Yan Huang, Xin Shan, Xiao Sun, Xinlei Wang, Xiaoyan Wang, Lingxin Chen, Shui Yu   +7 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Proteome-metabolome profiling of wax gland complex reveals functional changes in honeybee, Apis mellifera L.

iScience
Summary: Wax gland complex (WGC) serves as the primary generator of beeswax; however, the dynamic biological function in wax secretion remains unclear. To elucidate the developmental mechanism of WGC, we conducted a comprehensive analysis to reveal the ...
Rumeng Xu, Beibei Ma, Yiying Yang, Xuancheng Dong, Jianke Li, Xiang Xu, Yu Fang   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and performance of a microelectromagnetic vibration-powered generator [PDF]

, 2005
In this paper we report on the design, simulation and initial results of a microgenerator, which converts external vibrations into electrical energy. Power is generated by means of electromagnetic transduction with static magnets positioned either side ...
M.J. Tudor, Roy, S, Tudor, M.J., White, N.M., Saha, C., Beeby, S P, S. Roy, Roy, S., S. Kulkarni, Tudor, M J, N.M. White, T. O'Donnell, Kulkarni, S., Beeby, S.P., S.P. Beeby, C. Saha, O'Donnell, T., White, N M, Koukharenko, E, Saha, C, Kulkarni, S, Koukharenko, E., O'Donnell, T, E. Koukharenko   +23 more
core   +2 more sources

An approach to calculate Franck-Condon factors involving anharmonic potentials using harmonic oscillator bases

Journal of Physics Communications
In this contribution a discrete variable representation (DVR) approach to calculate Franck-Condon factors (FCFs) is presented. The method is illustrated using a harmonic oscillator basis. The advantage of this approach is that it is possible to calculate
E Suárez, R Lemus
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The linear generator as integral component of an energy converter for electric vehicles [PDF]

, 2011
The system in which the linear generator (LG) is integrated is called free-piston linear generator (FPLG). He is able to convert chemical energy into electrical energy by using a combustion process.
Rinderknecht, Frank
core  

Development of a cantilever beam generator employing vibration energy harvesting

, 2006
This paper details the development of a generator based upon a cantilever beam inertial mass system which harvests energy from ambient environmental vibrations. The paper compares the predicted results from Finite Element Analysis (FEA) of the mechanical
Tudor, M.J., Beeby, S.P., O'Donnell, T., Roy, S., Torah, R.   +4 more
core   +1 more source