Results 101 to 110 of about 104,482 (285)

High harmonic generation from axial chiral molecules

Optics Express, 2017
Axial chiral molecules, whose stereogenic element is an axis rather than a chiral center, have attracted widespread interest due to their important application, such as asymmetric synthesis and chirality transfer. We investigate high harmonic generation from axial chiral molecules with bichromatic counterrotating circularly polarized laser fields. High
Dian, Wang, Xiaosong, Zhu, Xi, Liu, Liang, Li, Xiaofan, Zhang, Pengfei, Lan, Peixiang, Lu   +6 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Proteome-metabolome profiling of wax gland complex reveals functional changes in honeybee, Apis mellifera L.

iScience
Summary: Wax gland complex (WGC) serves as the primary generator of beeswax; however, the dynamic biological function in wax secretion remains unclear. To elucidate the developmental mechanism of WGC, we conducted a comprehensive analysis to reveal the ...
Rumeng Xu, Beibei Ma, Yiying Yang, Xuancheng Dong, Jianke Li, Xiang Xu, Yu Fang   +6 more
doaj   +1 more source

Multimodality Imaging Probe for Positron Emission Tomography and Fluorescence Imaging Studies

Molecular Imaging, 2014
Our goal is to develop multimodality imaging agents for use in cell tracking studies by positron emission tomography (PET) and optical imaging (OI).
Suresh K. Pandey, Jasmeet Kaur, Balu Easwaramoorthy, Ankur Shah, Robert Coleman, Jogeshwar Mukherjee   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

An approach to calculate Franck-Condon factors involving anharmonic potentials using harmonic oscillator bases

Journal of Physics Communications
In this contribution a discrete variable representation (DVR) approach to calculate Franck-Condon factors (FCFs) is presented. The method is illustrated using a harmonic oscillator basis. The advantage of this approach is that it is possible to calculate
E Suárez, R Lemus
doaj   +1 more source

In silico generation of novel, drug-like chemical matter using the LSTM neural network

, 2017
The exploration of novel chemical spaces is one of the most important tasks of cheminformatics when supporting the drug discovery process. Properly designed and trained deep neural networks can provide a viable alternative to brute-force de novo ...
Ertl, Peter, Lewis, Richard, Martin, Eric, Polyakov, Valery   +3 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Orthogonal Experiments on Ozone Oxidation Denitration of Sintering Flue Gas

E3S Web of Conferences, 2018
Ozone oxidation denitration process has become the most closely watched sintering flue gas denitration technology currently. In order to investigate the influence of different operating conditions on NO oxidation in practical engineering application of ...
Yang Yingxin, Zhong Lu, Xue Xueliang, Hu Jingling, Hu Xiaotu, Liu Yong   +5 more
doaj   +1 more source

Controlled Molecule Generator for Optimizing Multiple Chemical Properties. [PDF]

ACM CHIL 2021 (2021), 2021
Shin B, Park S, Bak J, Ho JC.
europepmc   +1 more source