Results 71 to 80 of about 104,482 (285)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Characteristics of the polymer transport in ratchet systems

open access: yes, 2010
Molecules with complex internal structure in time-dependent periodic potentials are studied by using short Rubinstein-Duke model polymers as an example.
J. Bang-Jensen   +7 more
core   +1 more source

One-Dimensional Toda Molecule. I: General Solution [PDF]

open access: yesProgress of Theoretical Physics, 1983
Summary: A mechanism is presented for producing explicitly the general solutions to the one-dimensional Toda molecule equations associated with the classical complex Lie algebras of rank \(N\): \(sl (N+1,\mathbb{C})\), \(so(2N+1,\mathbb{C})\), \(sp(N,\mathbb{C})\) and \(so (2N,\mathbb{C})\).
Farwell, Ruth, Minami, Masatsugu
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

pH-responsive hierarchical H2S-releasing nano-disinfectant with deep-penetrating and anti-inflammatory properties for synergistically enhanced eradication of bacterial biofilms and wound infection

open access: yesJournal of Nanobiotechnology, 2022
Background Methicillin-resistant Staphylococcus aureus (MRSA) biofilm-associated bacterial infection is the primary cause of nosocomial infection and has long been an ongoing threat to public health.
Yue Zhang   +8 more
doaj   +1 more source

High-resolution Infrared Spectroscopy of the v23 and v22 Vibrational Bands of Methyl Vinyl Ketone [PDF]

open access: yes, 2018
The high-resolution Infrared spectrum of methyl vinyl ketone (C4H6O) has been acquired in the region containing the v22 and v23 bands near 987 cm-1 and 1001cm-1, respectively, using a quantum cascade laser-based spectrometer.
Iranpour, Michael
core   +1 more source

Inelastic effects in molecular junctions in the Coulomb and Kondo regimes: Nonequilibrium equation-of-motion approach

open access: yes, 2007
Inelastic effects in the Coulomb blockade and Kondo regimes of electron transport through molecular junctions are considered within a simple nonequilibrium equation-of-motion (EOM) approach.
A. C. Hewson   +10 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The General Structure of Transfer RNA Molecules [PDF]

open access: yesProceedings of the National Academy of Sciences, 1974
The three-dimensional structure of yeast phenylalanine tRNA serves as a useful basis for understanding the tertiary structure of all tRNAs. A large number of tRNA sequences have been surveyed and some general conclusions are drawn. There are only a few regions in the molecule in which there are differences in the number of nucleotides; and the ...
S H, Kim   +7 more
openaire   +2 more sources

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