Results 101 to 110 of about 3,169,273 (304)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Strength Ratios of Diffuse Interstellar Bands in Slightly Reddened Objects
UniverseThe disk of the Milky Way fills the interstellar medium in the form of discrete clouds, many (∼30) light-years across. The average density of this medium is 1 hydrogen atom per cm3 (Oort limit), in the clouds—several dozen atoms, and between the clouds ...
Jacek Krełowski, Arkadii Bondar
doaj +1 more source
The immunoglobulin molecule [PDF]
Immunohematology, 1998 Antibodies, or immunoglobulins, have been used for many years in immunohematology and yet the complexity of these molecules is rarely considered. This review concentrates on IgG and IgM molecules, as these are most usually found in transfusion laboratories.
openaire +2 more sources
ac electric trap for ground-state molecules
, 2005 We here report on the realization of an electrodynamic trap, capable of trapping neutral atoms and molecules in both low-field and high-field seeking states.
Bethlem, H.L. +6 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The nature of condensed single molecules : local electronic and mechanical characteristics [PDF]
, 2014 In order to advance the performance of molecule based electronic devices a detailed and fundamental knowledge about the underlying physical aspects is mandatory.
Fremy, Sweetlana Deva
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Influence of Several Compounds and Drugs on the Renal Uptake of Radiolabeled Affibody Molecules
, 2020 Affibody molecules are the most studied class of engineered scaffold proteins (ESPs) in radionuclide molecular imaging. Attempts to use affibody molecules directly labelled with radiometals for targeted radionuclide therapy were hampered by the high ...
Altai, Mohamed, +8 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Dynamical crystal creation with polar molecules or Rydberg atoms in optical lattices
, 2010 We investigate the dynamical formation of crystalline states with systems of polar molecules or Rydberg atoms loaded into a deep optical lattice. External fields in these systems can be used to couple the atoms or molecules between two internal states ...
Schachenmayer, J. +7 more
core +1 more source