Results 81 to 90 of about 3,169,273 (304)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Graph representation of multi-dimensional materials

open access: yesJPhys Materials
The integration of graph-based representations with machine learning methodologies is transforming the landscape of material discovery, offering a flexible approach for modelling a variety of materials, from molecules and nanomaterials to expansive three-
Carina T Cai   +2 more
doaj   +1 more source

Ultracold Molecules: The Effect of Electromagnetic Fields [PDF]

open access: yes, 2010
There is great interest within the physics and chemistry communities in the properties of ultracold molecules. Electromagnetic fields can be used to create, trap, and modify the collisional dynamics of ultracold molecules, and thus the properties of ...
Wallis, Alisdair Owen Garnett   +1 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The ascent of molecules [PDF]

open access: yesNature Chemistry, 2013
A collection of articles in this issue focuses on the chemical origin of life — how simple molecules present on the early Earth could have evolved into the complex dynamic biochemistry that we know today.
openaire   +2 more sources

A storage ring for neutral molecules

open access: yes, 2005
Electrostatic hexapoles are common tools in physical chemistry for performing state-selection and focusing of molecules. A hexapole can be viewed as a 2D-trap for polar molecules in low-field seeking states.
Crompvoets, Floris M. H.   +14 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Network Pharmacology Approaches Used to Identify Therapeutic Molecules for Chronic Venous Disease Based on Potential miRNA Biomarkers

open access: yesJournal of Xenobiotics
Chronic venous disease (CVD) is a prevalent condition in adults, significantly affecting the global elderly population, with a higher incidence in women than in men.
Oscar Salvador Barrera-Vázquez   +2 more
doaj   +1 more source

In Silico Design of a Peptide Receptor for Dopamine Recognition

open access: yes, 2020
: Dopamine (DA) is an important neurotransmitter with a fundamental role in regulatory functions related to the central, peripheral, renal, and hormonal nervous systems.
Rodriguez Salazar, Luna   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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