Results 31 to 40 of about 4,907 (238)
We consider a dam-water system modeled as a fluid-structure interaction, specifically, a coupled hyperbolic second-order problem, formulated in terms of the displacement of the structure and the fluid pressure.
Ricardo Faria +2 more
doaj +1 more source
Functional Meyer-Tanaka Formula
The functional Ito formula, firstly introduced by Bruno Dupire for continuous semimartingales, might be extended in two directions: different dynamics for the underlying process and/or weaker assumptions on the regularity of the functional. In this paper,
Saporito, Yuri F.
core +1 more source
Partial Schauder estimates for second-order elliptic and parabolic equations: a revisit
Under various conditions, we establish Schauder estimates for both divergence and non-divergence form second-order elliptic and parabolic equations involving H\"older semi-norms not with respect to all, but only with respect to some of the independent ...
Dong, Hongjie, Kim, Seick
core +1 more source
A mollified Ensemble Kalman filter
It is well recognized that discontinuous analysis increments of sequential data assimilation systems, such as ensemble Kalman filters, might lead to spurious high frequency adjustment processes in the model dynamics.
Anderson +27 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
We consider the fractional Laplacian operator $(-\Delta)^s$ (let $ s \in (0,1) $) on Euclidean space and investigate the validity of the classical integration-by-parts formula that connects the $ L^2(\mathbb{R}^d) $ scalar product between a function and ...
Muratori, Matteo
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Gradient Navigation Model for Pedestrian Dynamics
We present a new microscopic ODE-based model for pedestrian dynamics: the Gradient Navigation Model. The model uses a superposition of gradients of distance functions to directly change the direction of the velocity vector.
Dietrich, Felix, Köster, Gerta
core +1 more source
Mollification and non-vanishing of automorphic L-functions On GL(3) [PDF]
We prove a non-vanishing result for central values of $L$-functions on GL(3), by using the mollification method and the Kuznetsov trace formula.
Huang, Bingrong, Liu, Shenhui, Xu, Zhao
openaire +2 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source

