Results 151 to 160 of about 95,145 (229)

Oncogenic BRAF and KRAS Promote Global DNA Hypomethylation Through a Directed Pathway That Upregulates TET3

Cancer Science, Volume 117, Issue 9, Page 2397-2412, September 2026.
Oncogenic BRAF and KRAS promote global DNA hypomethylation through a directed pathway that increases the levels of TET3, which helps drive tumorigenesis. ABSTRACT Aberrant epigenetic modification is one of the characteristics of the cancer genome.
Ichiro Onoyama, W. Rod Hardy, Shoichiro Takeishi, Lihua Julie Zhu, Yanglan Tan, Lloyd Hutchinson, Jianhong Ou, Leyuan Ma, Ching‐Man Virbasius, Masafumi Yasunaga, Keiichi I. Nakayama, Scott A. Shaffer, Michael R. Green   +12 more
wiley   +1 more source

Unravelling Catalytic Divergence in Mo- and Fe-Only Nitrogenases: The Role of the Heterometal-Site and Protein Environment from QM/MM Insights. [PDF]

J Am Chem Soc
Joyce JP, Bjornsson R, DeBeer S.
europepmc   +1 more source

ADSC‐Derived CCL8 Regulates HIF‐1α Signaling and Promotes Colorectal Cancer Progression in a 3D Coculture Platform

Cancer Science, Volume 117, Issue 9, Page 2480-2495, September 2026.
Schematic illustration showing how CRC‐associated ADSC‐derived CCL8 promotes colorectal cancer cell migration through ERK/HIF‐1α signaling in a 3D coculture platform. ABSTRACT This study aimed to recapitulate adipose‐tumor interactions within the colorectal cancer (CRC) tumor microenvironment (TME) and to elucidate the role of adipose‐derived stem ...
Jeong‐Eun Yun, Yeseon Son, Jieun Seo, Ki Yong Hong, Junji Fukuda, Do‐Won Jeong, Jong‐Wan Park, Yang‐Sook Chun   +7 more
wiley   +1 more source

The Influence of Heterometals on Dinitrogen Binding at Synthetic Iron-Sulfur Clusters. [PDF]

Chem
Wu T, Ehweiner M, Brown AC, McSkimming A, Suess DLM.   +4 more
europepmc   +1 more source

Molybdenum Cofactor Deficiency [PDF]

, 2012
openaire   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, Volume 293, Issue 17, Page 5149-5169, September 2026.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Heavy Metals in Agriculture: Sources, Industrial Applications, Plant Toxicity, and Remediation Approaches. [PDF]

Int J Mol Sci
Khan MM, Qiu B, Zhu Z.
europepmc   +1 more source

Estimation of chloroplast macromolecular complex copy numbers and subunit stoichiometries during the Chlamydomonas reinhardtii cell cycle

The Plant Journal, Volume 127, Issue 5, September 2026.
SUMMARY An unbiased, quantitative view of biomolecules in a living cell is a prerequisite for accurate modeling approaches and informs our understanding of cellular metabolism at scale. In this work, we used the total protein approach (TPA), in which the total protein mass of a given proteomics sample is used as a calibrator for absolute protein ...
Stefan Schmollinger, Daniela Strenkert, Samuel O. Purvine, Carrie D. Nicora, Eric Soubeyrand, Gilles J. Basset, Sabeeha S. Merchant   +6 more
wiley   +1 more source

Magnetic interactions between metal sites in complex enzymes. [PDF]

J Biol Inorg Chem
Maiti BK, Moura I, Moura JJG.
europepmc   +1 more source

Assessment of Phenotype, Oxidative Stress and Biomacromolecule Oxidation in Human Chronic Skin Wound Epidermis in Active Debridement Tissue Versus Endstage Wounds

Wound Repair and Regeneration, Volume 34, Issue 5, September/October 2026.
ABSTRACT Impairment of cutaneous healing occurs in association with numerous comorbidities including diabetes, vascular insufficiency and immobility. Standard management of chronic wounds includes removal of necrotic tissue and infection management, but no biomarkers are used to guide appropriate debridement distance.
Dylan Tinney, Justin Carmichael, Punkuj Chawla, David Keast, Douglas W. Hamilton   +4 more
wiley   +1 more source