Results 11 to 20 of about 649,858 (244)
Spectroscopic Studies of Mononuclear Molybdenum Enzyme Centers [PDF]
Molecules, 2022 A concise review is provided of the contributions that various spectroscopic methods have made to our understanding of the physical and electronic structures of mononuclear molybdenum enzymes.
Martin L. Kirk, Russ Hille
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Future Journal of Pharmaceutical Sciences, 2015 Background: Molybdenum hydroxylases have been implicated as key oxidative enzymes in some diseases. Methods: Twenty 2-(substituted-thio)-quinazolin-4-one derivatives recently synthesized in our laboratory were examined for their inhibitory activity ...
Hussein I. El-Subbagh +3 more
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Cytotoxicity of iron (III), molybdenum (III), and their mixtures in BALB/3T3 and HepG2 cells
Journal of Veterinary Research, 2018 Introduction: Iron and molybdenum are essential trace elements for cell metabolism. They are involved in maintaining proper functions of enzymes, cell proliferation, and metabolism of DNA.
Terpiłowska Sylwia +2 more
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The Final Step in Molybdenum Cofactor Biosynthesis—A Historical View
MoleculesMolybdenum (Mo) is an essential micronutrient across all kingdoms of life, where it functions as a key component of the active centers of molybdenum-dependent enzymes.
Ralf R. Mendel, Kevin D. Oliphant
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Making Moco: A Personal History
Molecules, 2023 This contribution describes the path of my nearly forty-year quest to understand the special ligand coordinated to molybdenum and tungsten ions in their respective enzymes.
Sharon J. Nieter Burgmayer
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Frontiers in Genetics, 2021 Background: The molybdenum cofactor (Moco) deficiency in humans results in the inactivity of molybdenum-dependent enzymes and is caused by pathogenic variants in MOCS1 (Molybdenum cofactor synthesis 1), MOCS2 (Molybdenum cofactor synthesis 2), and GPHN ...
Qi Tian +12 more
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Molybdenum – a scoping review for Nordic Nutrition Recommendations 2023
Food & Nutrition Research, 2023 Molybdenum is an essential element in the form of the molybdenum cofactor (Moco). In humans, Moco is required for four enzymes: xanthine oxidase (XO), aldehyde oxidase, sulfite oxidase (SO), and mitochondrial amidoxime-reducing component (mARC).
Agneta Oskarsson, Maria Kippler
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Bringing Nitric Oxide to the Molybdenum World—A Personal Perspective
Molecules, 2023 Molybdenum-containing enzymes of the xanthine oxidase (XO) family are well known to catalyse oxygen atom transfer reactions, with the great majority of the characterised enzymes catalysing the insertion of an oxygen atom into the substrate. Although some
Luisa B. Maia
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Metal-Containing Formate Dehydrogenases, a Personal View
Molecules, 2023 Mo/W-containing formate dehydrogenases (FDH) catalyzes the reversible oxidation of formate to carbon dioxide at their molybdenum or tungsten active sites.
Silke Leimkühler
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Advancing Our Understanding of Pyranopterin-Dithiolene Contributions to Moco Enzyme Catalysis
Molecules, 2023 The pyranopterin dithiolene ligand is remarkable in terms of its geometric and electronic structure and is uniquely found in mononuclear molybdenum and tungsten enzymes.
Sharon J. Nieter Burgmayer +1 more
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