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The History of Animal and Plant Sulfite Oxidase—A Personal View
Sulfite oxidase is one of five molybdenum-containing enzymes known in eukaryotes where it catalyzes the oxidation of sulfite to sulfate. This review covers the history of sulfite oxidase research starting out with the early years of its discovery as a ...
Guenter Schwarz +2 more
exaly +3 more sources
Sulfite oxidase deficiency in a newborn
Isolated sulfite oxidase deficiency is a rare, autosomal recessive disease with a very poor prognosis. This condition usually presents in the neonatal period and is mainly characterized by neurological abnormalities, including refractory seizures ...
H Westerlinck +3 more
doaj +5 more sources
Increasing plant tolerance to sulfites/SO2 can lead to the development of tolerant crops to biotic and abiotic stresses. Plant sulfite oxidase (SO) is a molybdo-enzyme that oxidizes excess SO2/sulfite into non-toxic sulfate.
Moshe Sagi +2 more
exaly +3 more sources
Effect of sulfite on macrophage functions of normal and sulfite oxidase-deficient rats
Sulfite has both an endogenous and an exogenous provenance in the mammalian tissues. The aim of the present study was to assess the effect of sulfite on macrophages functions in normal or sulfite oxidase deficient rats. Rats were divided into eight groups; (1) control group, (2) sulfite group (the rats received sodium meta bi-sulfite (25 mg/kg) in ...
Vural Küçükatay +2 more
exaly +6 more sources
The role of glutamate oxaloacetate transaminases in sulfite biosynthesis and H2S metabolism
Molybdenum cofactor deficiency and isolated sulfite oxidase deficiency are two rare genetic disorders that are caused by impairment of the mitochondrial enzyme sulfite oxidase.
Anna-Theresa Mellis +8 more
doaj +1 more source
Isolated sulfite oxidase deficiency (ISOD) is a rare autosomal recessive neuro-metabolic disorder caused by a mutation in the sulfite oxidase (SUOX) gene situated on chromosome 12. Due to the deficiency of this mitochondrial enzyme (sulfite oxidase), the
Niamh McSweeney +6 more
doaj +1 more source
Severe isolated sulfide oxidase deficiency with a novel mutation
Background. Isolated sulfite oxidase deficiency (ISOD), caused by mutations in SUOX gene, is an autosomal recessive disease manifesting with early onset seizures, developmental delay, microcephaly, and spasticity.
Meriç Ergene +6 more
doaj +1 more source
Molecular Basis of Sulfite Oxidase Deficiency from the Structure of Sulfite Oxidase [PDF]
The molybdenum-containing enzyme sulfite oxidase catalyzes the conversion of sulfite to sulfate, the terminal step in the oxidative degradation of cysteine and methionine. Deficiency of this enzyme in humans usually leads to major neurological abnormalities and early death.
Kisker, Caroline +7 more
openaire +2 more sources
Overexpression of a maize sulfite oxidase gene in tobacco enhances tolerance to sulfite stress via sulfite oxidation and CAT-mediated H2O2 scavenging. [PDF]
Sulfite oxidase (SO) plays an important role in sulfite metabolism. To date, the molecular mechanisms of sulfite metabolism in plants are largely unknown.
Zongliang Xia +5 more
doaj +1 more source
Level of Sulfite Oxidase Activity Affects Sulfur and Carbon Metabolism in Arabidopsis
Molybdenum cofactor containing sulfite oxidase (SO) enzyme is an important player in protecting plants against exogenous toxic sulfite. It was also demonstrated that SO activity is essential to cope with rising dark-induced endogenous sulfite levels and ...
Dinara Oshanova +7 more
doaj +1 more source

