Results 41 to 50 of about 184 (130)

The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia

open access: yesNature Communications, 2018
In Drosophila, ensheathing glia encase the neuropil but their function is not well understood. Here the authors show a surprising role of ensheathing glia in regulating glutamate homeostasis and locomotion which is controlled by the sulfite oxidase ...
Nils Otto   +14 more
doaj   +1 more source

MoS2-based nanocomposites for cancer diagnosis and therapy

open access: yesBioactive Materials, 2021
Molybdenum is a trace dietary element necessary for the survival of humans. Some molybdenum-bearing enzymes are involved in key metabolic activities in the human body (such as xanthine oxidase, aldehyde oxidase and sulfite oxidase). Many molybdenum-based
Jianling Wang   +10 more
doaj   +1 more source

Isolated sulfite oxidase deficiency: a founder mutation [PDF]

open access: yesMolecular Case Studies, 2020
Isolated sulfite oxidase deficiency is a rare autosomal recessive inborn error of sulfur metabolism. Clinical features generally include devastating neurologic dysfunction, ectopia lentis, and increased urinary excretion of sulfite, thiosulfate, and S-sulfocysteine.
Mhanni, Aizeddin A   +5 more
openaire   +3 more sources

Advancing the Resolution of the Sulfur Compound Disproportionation Puzzle in Dissulfuribacter Thermophilus S69ᵀ Through Quantitative Label‐Free Comparative Proteomics

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 4, August 2026.
To date, only three microorganisms have been functionally characterised for sulfur disproportionation. Our work identifies a fourth example and provides novel proteomic insights into its underlying pathways. These findings advance our understanding of microbial sulfur catabolism and highlight the ecological role of D.
Marilina Fernandez   +8 more
wiley   +1 more source

Beyond Moco Biosynthesis―Moonlighting Roles of MoaE and MOCS2

open access: yesMolecules, 2022
Molybdenum cofactor (Moco) biosynthesis requires iron, copper, and ATP. The Moco-containing enzyme sulfite oxidase catalyzes terminal oxidation in oxidative cysteine catabolism, and another Moco-containing enzyme, xanthine dehydrogenase, functions in ...
Tamaki Suganuma
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, Volume 16, Issue 7, Page 1314-1327, July 2026.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Effect of l‐Cysteine on Enzymatic Browning, Antioxidant Activity, and GSH Stability in Fresh‐Cut Quince: A Comparative Evaluation With Potassium Metabisulfite

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
This study investigates the effectiveness of l‐cysteine and sodium metabisulfite (1% solutions) in reducing enzymatic browning and preserving antioxidant properties in fresh‐cut quince slices stored at 4°C for 9 days. l‐cysteine proved more effective than sodium metabisulfite in maintaining color brightness and enhancing antioxidant activity by ...
Omca Demirkol   +2 more
wiley   +1 more source

Screening of a clinically and biochemically diagnosed SOD patient using exome sequencing: A case report with a mutations/variations analysis approach

open access: yesEgyptian Journal of Medical Human Genetics, 2016
Background: Sulfite oxidase deficiency (SOD) is a rare neurometabolic inherited disorder causing severe delay in developmental stages and premature death.
Mohamad-Reza Aghanoori   +3 more
doaj   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva   +5 more
wiley   +1 more source

Overexpression of the Maize Sulfite Oxidase Increases Sulfate and GSH Levels and Enhances Drought Tolerance in Transgenic Tobacco

open access: yesFrontiers in Plant Science, 2018
Sulfite oxidase (SO) plays a pivotal role in sulfite metabolism. In our previous study, sulfite-oxidizing function of the SO from Zea mays (ZmSO) was characterized. To date, the knowledge of ZmSO’s involvement in abiotic stress response is scarce.
Zongliang Xia   +4 more
doaj   +1 more source

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