Results 201 to 210 of about 5,659 (287)

AI‐Driven Acceleration of Fluorescence Probe Discovery

Advanced Science, EarlyView.
We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang, Yanbo Li, Xue Tian, Sen Yang, Ruina Luo, Cenxing Zhou, Yuxuan Liu, Jingying Hu, Sen Feng, Lu Gan, Chongzhao Ran, Kun‐Hsing Yu, Junhan Zhao, Xiao Han, Xuan Zhai, Yuntao Jia, Jiapei Dai, Xiyue Wang, Biyue Zhu   +18 more
wiley   +1 more source

Experimental and Mechanistic Study on Flotation Separation of Chalcopyrite and Molybdenite Using the Novel Depressant 2-Mercapto-6-Methylpyrimidin-4-ol. [PDF]

Molecules
Lv X, Luo A, Tong X, Chen J, Jian S.
europepmc   +1 more source

Enhanced Recovery of Copper and Molybdenum from Concentrator Tailings using Dithiopyrylmethane (DTM) as a Novel Selective Collector

Nishonbek Kenjayev, Mansurjon Xolmatov
openalex   +1 more source

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Advanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo   +7 more
wiley   +1 more source

Effects of restoration duration on plant community and soil chemical stoichiometry characteristics in mine waste dumps. [PDF]

Front Plant Sci
Shao Y, Zuo H, Ma Y, Ma X, Li G.
europepmc   +1 more source

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

Advanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son, Goeun Kim, Jungjoon K. Lee   +2 more
wiley   +1 more source

Study on the Properties of Gypsum-based Self-leveling Mortar using Molybdenum Tailings

, 2019
Jixiu Zhang, Ye Zhang, Jikang Liu, Yuanchao Miao   +3 more
openalex   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Molybdenum-Induced Oxidative and Inflammatory Injury and Metabolic Pathway Disruption in Goat Pancreas. [PDF]

Metabolites
Li L, Ran Y, Shen X.
europepmc   +1 more source

Pollution control and metal resource recovery for acid mine drainage [PDF]

, 2014
Chen, Tao, Lei, Chang, Xiao, Xianming, Yan, Bo   +3 more
core   +1 more source