Results 91 to 100 of about 1,518,720 (358)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Gompertz Inverted Nadarajah-Haghighi (GoINH) Distribution Properties with Application to real data

open access: yesTikrit Journal of Administrative and Economic Sciences
Over the past years, many academics in mathematical statistics have introduced new continuous distributions to respond to real-world data growth, and this adaptability or flexibility has become essential to this development.
Dalya Dh. Ahmed, Mundher A. Khaleel
doaj   +1 more source

Exp-Kumaraswamy Distributions: Some Properties and Applications [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2015
In this paper, we propose and study exp-kumaraswamy distribution. Some of its properties  are derived, including the density function, hazard rate function, quantile function, moments,  skewness  and kurtosis.
Z. Javanshiri   +2 more
doaj  

On powers of Stieltjes moment sequences, II

open access: yes, 2004
We consider the set of Stieltjes moment sequences, for which every positive power is again a Stieltjes moment sequence, we and prove an integral representation of the logarithm of the moment sequence in analogy to the L\'evy-Khinchin representation.
Berg, Christian
core   +1 more source

Moment generating function of a first hitting place for the integrated Ornstein-Uhlenbeck process

open access: yes, 1989
We consider the two-dimensional process (x(t),y(t)), where y(t)=dx(t)/dt is an Ornstein-Uhlenbeck process, Let T be the smallest t for which y(t) = [upsilon].
M. Lefebvre
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

On Properties of the Hyperbolic Distribution

open access: yesMathematics
This paper is set to analytically describe properties of the hyperbolic distribution. This law, along with the variance-gamma distribution, is one of the most popular normal mean–variance mixtures from the point of view of various applications.
Roman V. Ivanov
doaj   +1 more source

Generalized moments of additive functions

open access: yesJournal of Number Theory, 1984
AbstractElliott's generalization of the Turán-Kubilius inequality is further generalized by establishing an upper bound for the sum Σn≤xF(∣f(n) − A∣), where f is a complex-valued additive arithmetical function, A an arbitrary number and F an arbitrary nonnegative-valued increasing function.
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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