Results 131 to 140 of about 79,797 (290)
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Potentials of mountainous region of Serbia for map sector development
Ekonomika Poljoprivrede (1979), 2010 Apart from mineral row material and energetic resources, soil quality, relief characteristics and hydro-potentials, natural resources also comprises for landscape characteristics as well as geographic position and biological diversity.
Svetlana Turudija Živanović +2 more
doaj
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Moment maps, symplectomorphism groups and compatible complex structures [PDF]
, 2005 Miguel Abreu +2 more
openalex +3 more sources
Nontrivial examples of coupled equations for Kähler metrics and Yang-Mills connections
Open Mathematics, 2012 Keller Julien +1 more
doaj +1 more source
“Hypermultiplet structures” and moment maps for generalised diffeo- morphisms
, 2014 Daniel Waldram
openalex +1 more source
Koszul properties of the moment map of some classical representations [PDF]
, 2017 Aldo Conca +2 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source