Results 91 to 100 of about 2,692,899 (243)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Sieving parton distribution function moments via the moment problem

Physics Letters B
We apply a classical mathematical problem, the moment problem, with its related mathematical achievements, to the study of the parton distribution function (PDF) in hadron physics, and propose a strategy to sieve the moments of the PDF by exploiting its ...
Xiaobin Wang, Minghui Ding, Lei Chang
doaj   +1 more source

Search for electric dipole moments in storage rings

EPJ Web of Conferences, 2016
The JEDI collaboration aims at making use of storage ring to provide the most precise measurement of the electric dipole moments of hadrons. The method makes exploits a longitudinal polarized beam. The existence an electric dipole moment would generate a
Lenisa Paolo
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Neutrino magnetic moments: effective versus fundamental parameters

Nuclear Physics B
The search for neutrino magnetic moments offers a valuable window into physics beyond the Standard Model. However, a common misconception arises in the interpretation of experimental results: the assumption that the so-called effective neutrino magnetic ...
Christoph A. Ternes, Mariam Tórtola
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Fermilab muon g-2 experiment

EPJ Web of Conferences, 2018
The Fermilab muon g-2 experiment will measure the muon anomalous magnetic moment aμ to 140 ppb – a four-fold improvement over the earlier Brookhaven experiment.
Gorringe Tim
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Workshop summary: Kaons@CERN 2023

European Physical Journal C: Particles and Fields
Kaon physics is at a turning point – while the rare-kaon experiments NA62 and KOTO are in full swing, the end of their lifetime is approaching and the future experimental landscape needs to be defined.
G. Anzivino, Sergio Arguedas Cuendis, V. Bernard, J. Bijnens, B. Bloch-Devaux, M. Bordone, F. Brizioli, J. Brod, J. M. Camalich, A. Ceccucci, P. Cenci, N. H. Christ, G. Colangelo, C. Cornella, A. Crivellin, G. D’Ambrosio, F. F. Deppisch, A. Dery, F. Dettori, M. Di Carlo, B. Döbrich, J. Engelfried, R. Fantechi, M. González-Alonso, M. Gorbahn, E. Goudzovski, Y. Grossman, N. Hermansson-Truedsson, Z. Hives, M. Hoferichter, B.-L. Hoid, T. Husek, G. Isidori, A. Jüttner, K. Kampf, S. Kholodenko, M. Knecht, M. Kolesár, M. Koval, C. Lazzeroni, Z. Ligeti, F. Mahmoudi, R. Marchevski, Diego Martínez Santos, K. Massri, T. Mombächer, H. Nanjo, S. Neshatpour, T. Nomura, E. Passemar, L. Peruzzo, M. Piccini, A. Pich, C. T. Sachrajda, S. Schacht, K. Shiomi, P. Stangl, P. Stoffer, J. Swallow, J. T. Tsang, G. Valencia, R. Wanke, J. Zupan   +62 more
doaj   +1 more source