Results 31 to 40 of about 251,836 (304)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

PROBLEM OF PLATE BENDING IN THE MOMENT ASYMMETRIC THEORY OF ELASTICITY

International Journal for Computational Civil and Structural Engineering, 2023
For a number of materials used in modern practice, calculations according to the classical theory of elasticity give incorrect results. To ensure the reliable operation of structures, there is a need for new theories.
Nelly Rogacheva, Yulia Zheglova
doaj   +1 more source

On a Nonlinear Moments Problem

Journal of Mathematical Analysis and Applications, 1993
The author investigates the problem to determine a function \(u\in C[a,b]\) if the value of the integral \[ I(g;u):=\int^ b_ ag(u(x))dx \] is known for all \(g\in C(\mathbb{R})\) or only those \(g\) belonging to some countable subset of \(C(\mathbb{R})\). Actually, the existence of a bounded-variation function \(\mu(x;u)\) with \[ I(g;u)={1\over 2\sqrt\
openaire   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Functional generalized empirical likelihood estimation for conditional moment restrictions [PDF]

, 2022
Important problems in causal inference, economics, and, more generally, robust machine learning can be expressed as conditional moment restrictions, but estimation becomes challenging as it requires solving a continuum of unconditional moment ...
Muandet, Krikamol, Kremer, Heiner, Zhu, Jia-Jie, Schölkopf, Bernhard   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Covariance Realization Problem for Spin Systems [PDF]

, 2013
Let (Ω, Α) be a measurable space, F be a family of measurable functions f from Ω to R, and c: F→R be a given function. A generalized moment problem consists of finding all probabilities P on (Ω, Α) such that ∫ f dP = c(f) = cf for all f є F, and in ...
Sahasrabudhe, Neeraja
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A note on the general moment problem [PDF]

Opuscula Mathematica
In this note we show that given an indeterminate Hamburger moment sequence, it is possible to perturb the first moment in such way that the obtained sequence remains an indeterminate Hamburger moment sequence.
Hamza El Azhar, Abdelouahab Hanine, El Hassan Zerouali   +2 more
doaj   +1 more source

The tracial moment problem on quadratic varieties

, 2022
The truncated moment problem asks to characterize finite sequences of real numbers that are the moments of a positive Borel measure on Rn. Its tracial analog is obtained by integrating traces of symmetric matrices and is the main topic of this article ...
Bhardwaj, Abhishek, Zalar, Aljaž
core   +1 more source