Results 41 to 50 of about 2,627,314 (278)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Moment-Based Relaxation of the Optimal Power Flow Problem

open access: yes, 2014
The optimal power flow (OPF) problem minimizes power system operating cost subject to both engineering and network constraints. With the potential to find global solutions, significant research interest has focused on convex relaxations of the non-convex
Hiskens, Ian A., Molzahn, Daniel K.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A note on the general moment problem [PDF]

open access: yesOpuscula Mathematica
In this note we show that given an indeterminate Hamburger moment sequence, it is possible to perturb the first moment in such way that the obtained sequence remains an indeterminate Hamburger moment sequence.
Hamza El Azhar   +2 more
doaj   +1 more source

PROBLEM OF PLATE BENDING IN THE MOMENT ASYMMETRIC THEORY OF ELASTICITY

open access: yesInternational Journal for Computational Civil and Structural Engineering, 2023
For a number of materials used in modern practice, calculations according to the classical theory of elasticity give incorrect results. To ensure the reliable operation of structures, there is a need for new theories.
Nelly Rogacheva, Yulia Zheglova
doaj   +1 more source

Moment problem for symmetric algebras of locally convex spaces

open access: yes, 2018
It is explained how a locally convex (lc) topology $\tau$ on a real vector space $V$ extends to a locally multiplicatively convex (lmc) topology $\overline{\tau}$ on the symmetric algebra $S(V)$.
Ghasemi, M.   +3 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The operator approach to the truncated multidimensional moment problem

open access: yesConcrete Operators, 2019
We study the truncated multidimensional moment problem with a general type of truncations. The operator approach to the moment problem is presented. The case where the associated operators form a commuting self-adjoint tuple is characterized in terms of ...
Zagorodnyuk Sergey M.
doaj   +1 more source

Plate-Like Flexible Spacecraft Modeling and Distribution of Control Moment Gyroscopes

open access: yesSpace: Science & Technology, 2023
This study investigates the optimization configuration problem of control moment gyroscopes for flexible vibration suppression of large space structures.
Jingyu Guo   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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