Results 51 to 60 of about 2,627,314 (278)
Strong CP problem, electric dipole moment, and fate of the axion
SciPost Physics Proceedings, 2022 Three hard problems! In this talk I investigate the long-distance properties of quantum chromodynamics in the presence of a topological theta term. This is done on the lattice, using the gradient flow to isolate the long-distance modes in the functional ...
Gerrit Schierholz
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
NCoder—a quantum field theory approach to encoding data
Machine Learning: Science and TechnologyIn this paper we present a novel approach to interpretable AI inspired by quantum field theory which we call the NCoder . The NCoder is a modified autoencoder neural network whose latent layer is prescribed to be a subset of n -point correlation ...
D S Berman, M S Klinger, A G Stapleton
doaj +1 more source
Heavy-tailed Independent Component Analysis
, 2015 Independent component analysis (ICA) is the problem of efficiently recovering a matrix $A \in \mathbb{R}^{n\times n}$ from i.i.d. observations of $X=AS$ where $S \in \mathbb{R}^n$ is a random vector with mutually independent coordinates. This problem has
Anderson, Joseph +3 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
PAMM, 2014 AbstractThe work is devoted to the local moment problem, which consists in finding of non‐decreasing functions on the real axis having given first 2n + 1, n ≥ 0, power moments on the whole axis and also 2m + 1 first power moments on a certain finite axis interval.
Adamyan, Vadym +1 more
openaire +2 more sources
A Strong Stieltjes Moment Problem [PDF]
Transactions of the American Mathematical Society, 1980 This paper is concerned with double sequences of complex numbers C = { c n } − ∞ ∞ C\, = \,\{ {c_n}\} _{ - \infty }^\infty and with formal Laurent series
Jones, William B. +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source